PMID- 28951948 OWN - NLM STAT- MEDLINE DCOM- 20180727 LR - 20220409 IS - 1432-1998 (Electronic) IS - 0301-0449 (Linking) VI - 48 IP - 1 DP - 2018 Jan TI - A comparison study of size-specific dose estimate calculation methods. PG - 56-65 LID - 10.1007/s00247-017-3986-7 [doi] AB - BACKGROUND: The size-specific dose estimate (SSDE) has emerged as an improved metric for use by medical physicists and radiologists for estimating individual patient dose. Several methods of calculating SSDE have been described, ranging from patient thickness or attenuation-based (automated and manual) measurements to weight-based techniques. OBJECTIVE: To compare the accuracy of thickness vs. weight measurement of body size to allow for the calculation of the size-specific dose estimate (SSDE) in pediatric body CT. MATERIALS AND METHODS: We retrospectively identified 109 pediatric body CT examinations for SSDE calculation. We examined two automated methods measuring a series of level-specific diameters of the patient's body: method A used the effective diameter and method B used the water-equivalent diameter. Two manual methods measured patient diameter at two predetermined levels: the superior endplate of L2, where body width is typically most thin, and the superior femoral head or iliac crest (for scans that did not include the pelvis), where body width is typically most thick; method C averaged lateral measurements at these two levels from the CT projection scan, and method D averaged lateral and anteroposterior measurements at the same two levels from the axial CT images. Finally, we used body weight to characterize patient size, method E, and compared this with the various other measurement methods. Methods were compared across the entire population as well as by subgroup based on body width. RESULTS: Concordance correlation (rho(c)) between each of the SSDE calculation methods (methods A-E) was greater than 0.92 across the entire population, although the range was wider when analyzed by subgroup (0.42-0.99). When we compared each SSDE measurement method with CTDI(vol,) there was poor correlation, rho(c)<0.77, with percentage differences between 20.8% and 51.0%. CONCLUSION: Automated computer algorithms are accurate and efficient in the calculation of SSDE. Manual methods based on patient thickness provide acceptable dose estimates for pediatric patients <30 cm in body width. Body weight provides a quick and practical method to identify conversion factors that can be used to estimate SSDE with reasonable accuracy in pediatric patients with body width >/=20 cm. FAU - Parikh, Roshni A AU - Parikh RA AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. AD - Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA. FAU - Wien, Michael A AU - Wien MA AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. michael.wien@uhhospitals.org. FAU - Novak, Ronald D AU - Novak RD AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. AD - Center for Mitochondrial Medicine Research, Rebecca D. Considine Research Institute, Children's Hospital Medical Center of Akron, Akron, OH, USA. FAU - Jordan, David W AU - Jordan DW AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. FAU - Klahr, Paul AU - Klahr P AD - CT Clinical Science, Philips Healthcare, Highland Heights, OH, USA. FAU - Soriano, Stephanie AU - Soriano S AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. AD - Department of Radiology, University of Washington, Seattle, WA, USA. FAU - Ciancibello, Leslie AU - Ciancibello L AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. FAU - Berlin, Sheila C AU - Berlin SC AD - Department of Radiology, Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave., Cleveland, OH, 44106, USA. LA - eng PT - Comparative Study PT - Journal Article DEP - 20170927 PL - Germany TA - Pediatr Radiol JT - Pediatric radiology JID - 0365332 SB - IM MH - Adolescent MH - *Algorithms MH - *Body Size MH - *Body Weight MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Infant MH - Male MH - *Radiation Dosage MH - Retrospective Studies MH - Risk MH - *Tomography, X-Ray Computed MH - Young Adult OTO - NOTNLM OT - Children OT - Computed tomography OT - Radiation dose OT - Size-specific dose estimate EDAT- 2017/09/28 06:00 MHDA- 2018/07/28 06:00 CRDT- 2017/09/28 06:00 PHST- 2017/01/18 00:00 [received] PHST- 2017/09/06 00:00 [accepted] PHST- 2017/06/20 00:00 [revised] PHST- 2017/09/28 06:00 [pubmed] PHST- 2018/07/28 06:00 [medline] PHST- 2017/09/28 06:00 [entrez] AID - 10.1007/s00247-017-3986-7 [pii] AID - 10.1007/s00247-017-3986-7 [doi] PST - ppublish SO - Pediatr Radiol. 2018 Jan;48(1):56-65. doi: 10.1007/s00247-017-3986-7. Epub 2017 Sep 27.