PMID- 28955476 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220331 IS - 2055-1169 (Print) IS - 2055-1169 (Electronic) IS - 2055-1169 (Linking) VI - 3 IP - 2 DP - 2017 Jul-Dec TI - Periaortic lymphoma in a cat. PG - 2055116917729627 LID - 10.1177/2055116917729627 [doi] LID - 2055116917729627 AB - CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia. Clinicopathological investigations revealed non-regenerative anaemia (haematocrit 0.17 l/l; reference interval [RI] 0.24-0.45 l/l) and increased feline pancreatic lipase concentration (Spec fPL test [IDEXX] 8.3 mug/l; RI 0.1-3.5 mug/l). Feline leukaemia virus antigen and feline immunodeficiency virus antibody tests were negative. Thoracic and abdominal imaging revealed a soft tissue structure in the area of the thoracoabdominal aorta. CT confirmed a periaortic contrast-enhancing mass extending from the level of T9-L2, with associated intervertebral infiltration at the level of T11-T12. Post-mortem examination confirmed the presence of a solid, white, multinodular, well-demarcated mass encircling the aorta extending from T9-L2. Based on histopathology and immunohistochemistry, a diagnosis of B-cell lymphoma was made. Lymphoma was also identified histopathologically within the kidneys and spleen. Evidence of mild Wallerian degeneration was present within the spinal cord, indicating compression at the level of the periaortic mass. RELEVANCE AND NOVEL INFORMATION: To our knowledge, this is the first report of periaortic lymphoma in the cat. Although periaortic tumours are exceptionally rare in veterinary medicine, lymphoma should be considered as a differential in cats. FAU - Bree, Laura AU - Bree L AD - University College Dublin, Section of Veterinary Clinical Sciences, Dublin, Ireland. FAU - Bergamino, Chiara AU - Bergamino C AD - University College Dublin, Section of Veterinary Clinical Sciences, Dublin, Ireland. FAU - Mullins, Ronan AU - Mullins R AD - University College Dublin, Section of Veterinary Clinical Sciences, Dublin, Ireland. FAU - Kelly, Pamela AU - Kelly P AD - University College Dublin, Section of Veterinary Clinical Sciences, Dublin, Ireland. FAU - Shiel, Robert AU - Shiel R AD - University College Dublin, Section of Veterinary Clinical Sciences, Dublin, Ireland. LA - eng PT - Case Reports DEP - 20170918 PL - England TA - JFMS Open Rep JT - JFMS open reports JID - 101672978 PMC - PMC5607923 COIS- Conflict of interest: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2017/09/29 06:00 MHDA- 2017/09/29 06:01 PMCR- 2017/09/18 CRDT- 2017/09/29 06:00 PHST- 2017/09/29 06:00 [entrez] PHST- 2017/09/29 06:00 [pubmed] PHST- 2017/09/29 06:01 [medline] PHST- 2017/09/18 00:00 [pmc-release] AID - 10.1177_2055116917729627 [pii] AID - 10.1177/2055116917729627 [doi] PST - epublish SO - JFMS Open Rep. 2017 Sep 18;3(2):2055116917729627. doi: 10.1177/2055116917729627. eCollection 2017 Jul-Dec.