PMID- 28959533
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2214-7500 (Print)
IS  - 2214-7500 (Electronic)
IS  - 2214-7500 (Linking)
VI  - 3
DP  - 2016
TI  - Arsenic induced hematological and biochemical responses in nutritionally 
      important catfish Clarias batrachus (L.).
PG  - 148-152
LID - 10.1016/j.toxrep.2016.01.001 [doi]
AB  - The impact of sublethal toxicity of sodium arsenite on hematological and certain 
      biochemical parameters of the fresh water catfish Clarias batrachus has been 
      analyzed following exposure of sublethal concentration (1 mg/L; 5% of LC(50) 
      value) of sodium arsenite for 10, 30, 45, and 60 days. Arsenic bioaccumulation in 
      the blood tissue of the fish increased progressively with increased period of 
      exposure. The values of total erythrocyte count (TECs), total leucocytes count 
      (TLCs), hemoglobin concentration, and packed cell volume (PCV) 
      1.40 +/- 0.03 x 10(6)/mm(3), 174.83 +/- 2.74 x 10(3)/mm(3), 5.01 +/- 0.26 g/100 ml, 
      25.00 +/- 1.06 were observed respectively at the end of 60 days of exposure. The 
      results of hematological indices were found to be 179.23 +/- 8.81fl/cell for mean 
      corpuscular volume (MCV), 35.92 +/- 1.89 pg/cell for mean corpuscular hemoglobin 
      (MCH) and 20.17 +/- 1.12 g/dl for mean corpuscular hemoglobin concentration (MCHC). 
      The present findings are clearly indicating severe fish anemia due to the arsenic 
      salt exposure. The continued arsenic toxicity results in decreased serum protein 
      concentration that might be a cause for the loss of weight as well as weakness in 
      the fish.
FAU - Kumar, Randhir
AU  - Kumar R
AD  - Eco-physiology Unit, Department of Zoology, Banaras Hindu University, Varanasi 
      221 005, India.
FAU - Banerjee, T K
AU  - Banerjee TK
AD  - Eco-physiology Unit, Department of Zoology, Banaras Hindu University, Varanasi 
      221 005, India.
LA  - eng
PT  - Journal Article
DEP - 20160108
PL  - Ireland
TA  - Toxicol Rep
JT  - Toxicology reports
JID - 101630272
PMC - PMC5615784
OTO - NOTNLM
OT  - Cholesterol
OT  - Clarias batrachus
OT  - Hematological indices
OT  - Sodium arsenite
OT  - Toxicity
EDAT- 2016/01/08 00:00
MHDA- 2016/01/08 00:01
PMCR- 2016/01/08
CRDT- 2017/09/30 06:00
PHST- 2015/08/18 00:00 [received]
PHST- 2015/12/20 00:00 [revised]
PHST- 2016/01/04 00:00 [accepted]
PHST- 2017/09/30 06:00 [entrez]
PHST- 2016/01/08 00:00 [pubmed]
PHST- 2016/01/08 00:01 [medline]
PHST- 2016/01/08 00:00 [pmc-release]
AID - S2214-7500(16)30001-4 [pii]
AID - 10.1016/j.toxrep.2016.01.001 [doi]
PST - epublish
SO  - Toxicol Rep. 2016 Jan 8;3:148-152. doi: 10.1016/j.toxrep.2016.01.001. eCollection 
      2016.