PMID- 28959894
OWN - NLM
STAT- MEDLINE
DCOM- 20190220
LR  - 20191210
IS  - 2169-141X (Electronic)
IS  - 2169-1401 (Linking)
VI  - 46
IP  - 8
DP  - 2018 Dec
TI  - Hydrothermally synthesized zinc oxide nanorods incorporated on lab-on-paper 
      device for electrochemical detection of recreational drug.
PG  - 1586-1593
LID - 10.1080/21691401.2017.1381614 [doi]
AB  - This paper reports an electrochemical paper analytical device (EPAD) for 
      detection of recreational drug; methylenedioxymethamphetamine (MDMA). MDMA is 
      used as an addictive narcotic by youth and there is an urgent need to detect this 
      drug as it is a potential neurotoxic agent. The proposed EPAD represents many 
      advantageous features of being simple, low-cost, consistent and disposable. The 
      working electrode of the EPAD features zinc oxide nanorods (ZnONRs). The 
      morphological, optical, elemental composition and phase analysis of the 
      synthesized ZnONRs has been characterized by field emission scanning electron 
      microscopy (FESEM), UV-Vis spectroscopy, energy dispersive X-ray spectroscopy 
      (EDAX), photo-luminescence (PL) and X-ray diffraction (XRD). The developed sensor 
      showed optimum response at 7.0 pH and wide linear range of 1 microM-1 mM with a low 
      detection limit of 0.1 microM for MDMA. Evaluation of the sensor also revealed best 
      results in terms of analytical recovery (95%) and accuracy (95%). The designed 
      EPAD could prove to be very effective in case of forensic diagnostic 
      applications. This work provides a reliable diagnostic method for remote areas 
      with limited resources, and will also help people who cannot afford expensive 
      medical tests and have limited access to power and trained personnel.
FAU - Narang, Jagriti
AU  - Narang J
AD  - a Amity Institute of Nanotechnology , Amity University , Noida , UP , India.
FAU - Singhal, Chaitali
AU  - Singhal C
AD  - a Amity Institute of Nanotechnology , Amity University , Noida , UP , India.
FAU - Khanuja, Manika
AU  - Khanuja M
AD  - b Centre for Nanoscience and Nanotechnology , Jamia Millia Islamia , New Delhi , 
      India.
FAU - Mathur, Ashish
AU  - Mathur A
AD  - a Amity Institute of Nanotechnology , Amity University , Noida , UP , India.
FAU - Jain, Akshay
AU  - Jain A
AD  - a Amity Institute of Nanotechnology , Amity University , Noida , UP , India.
FAU - Pundir, C S
AU  - Pundir CS
AD  - c Department of Biochemistry , Maharishi Dayanand University , Rohtak , Haryana , 
      India.
LA  - eng
PT  - Journal Article
DEP - 20170929
PL  - England
TA  - Artif Cells Nanomed Biotechnol
JT  - Artificial cells, nanomedicine, and biotechnology
JID - 101594777
RN  - 0 (Illicit Drugs)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - SOI2LOH54Z (Zinc Oxide)
SB  - IM
MH  - Electrochemical Techniques/*methods
MH  - Humans
MH  - Illicit Drugs/*analysis
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*analysis
MH  - Nanotubes/*chemistry
MH  - Zinc Oxide/*chemistry
OTO - NOTNLM
OT  - EPAD
OT  - Recreational drug
OT  - amphetamine
OT  - methylenedioxymethamphetamine (MDMA)
OT  - point-of-care devices
EDAT- 2017/09/30 06:00
MHDA- 2019/03/21 06:00
CRDT- 2017/09/30 06:00
PHST- 2017/09/30 06:00 [pubmed]
PHST- 2019/03/21 06:00 [medline]
PHST- 2017/09/30 06:00 [entrez]
AID - 10.1080/21691401.2017.1381614 [doi]
PST - ppublish
SO  - Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):1586-1593. doi: 
      10.1080/21691401.2017.1381614. Epub 2017 Sep 29.