PMID- 28964621 OWN - NLM STAT- MEDLINE DCOM- 20181119 LR - 20190221 IS - 1873-4022 (Electronic) IS - 1873-4022 (Linking) VI - 43 IP - 3 DP - 2018 Autumn TI - AAA and AXB algorithms for the treatment of nasopharyngeal carcinoma using IMRT and RapidArc techniques. PG - 224-229 LID - S0958-3947(17)30100-0 [pii] LID - 10.1016/j.meddos.2017.08.009 [doi] AB - The aim of this study is to evaluate the impact of anisotropic analytical algorithm (AAA) and 2 reporting systems (AXB-D(m) and AXB-D(w)) of Acuros XB algorithm (AXB) on clinical plans of nasopharyngeal patients using intensity-modulated radiotherapy (IMRT) and RapidArc (RA) techniques. Six plans of different algorithm-technique combinations are performed for 10 patients to calculate dose-volume histogram (DVH) physical parameters for planning target volumes (PTVs) and organs at risk (OARs). The number of monitor units (MUs) and calculation time are also determined. Good coverage is reported for all algorithm-technique combination plans without exceeding the tolerance for OARs. Regardless of the algorithm, RA plans persistently reported higher D(2%) values for PTV-70. All IMRT plans reported higher number of MUs (especially with AXB) than did RA plans. AAA-IMRT produced the minimum calculation time of all plans. Major differences between the investigated algorithm-technique combinations are reported only for the number of MUs and calculation time parameters. In terms of these 2 parameters, it is recommended to employ AXB in calculating RA plans and AAA in calculating IMRT plans to achieve minimum calculation times at reduced number of MUs. CI - Copyright (c) 2017 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved. FAU - Kamaleldin, Maha AU - Kamaleldin M AD - Radiation Therapy Department, Faculty of Medicine, Cairo University, Cairo, Egypt. FAU - Elsherbini, Nader A AU - Elsherbini NA AD - Radiation Therapy Department, Faculty of Medicine, Cairo University, Cairo, Egypt. FAU - Elshemey, Wael M AU - Elshemey WM AD - Biophysics Department, Faculty of Science, Cairo University, Cairo, Egypt. Electronic address: welshemey@sci.cu.edu.eg. LA - eng PT - Journal Article DEP - 20170928 PL - United States TA - Med Dosim JT - Medical dosimetry : official journal of the American Association of Medical Dosimetrists JID - 8908862 SB - IM MH - Algorithms MH - Carcinoma/*radiotherapy MH - Humans MH - Nasopharyngeal Carcinoma MH - Nasopharyngeal Neoplasms/*radiotherapy MH - Radiotherapy Planning, Computer-Assisted/*methods MH - *Radiotherapy, Intensity-Modulated OTO - NOTNLM OT - AAA OT - AXB-D(m) OT - AXB-D(w) OT - IMRT OT - Nasopharyngeal carcinoma OT - RA OT - VMAT EDAT- 2017/10/02 06:00 MHDA- 2018/11/20 06:00 CRDT- 2017/10/02 06:00 PHST- 2017/07/02 00:00 [received] PHST- 2017/08/20 00:00 [revised] PHST- 2017/08/26 00:00 [accepted] PHST- 2017/10/02 06:00 [pubmed] PHST- 2018/11/20 06:00 [medline] PHST- 2017/10/02 06:00 [entrez] AID - S0958-3947(17)30100-0 [pii] AID - 10.1016/j.meddos.2017.08.009 [doi] PST - ppublish SO - Med Dosim. 2018 Autumn;43(3):224-229. doi: 10.1016/j.meddos.2017.08.009. Epub 2017 Sep 28.