PMID- 28982571 OWN - NLM STAT- MEDLINE DCOM- 20180611 LR - 20201216 IS - 1876-7591 (Electronic) IS - 1936-878X (Print) IS - 1876-7591 (Linking) VI - 10 IP - 10 Pt A DP - 2017 Oct TI - Role of Cardiac Magnetic Resonance in the Diagnosis and Prognosis of Nonischemic Cardiomyopathy. PG - 1180-1193 LID - S1936-878X(17)30776-3 [pii] LID - 10.1016/j.jcmg.2017.08.005 [doi] AB - Cardiac magnetic resonance (CMR) is a valuable tool for the evaluation of patients with, or at risk for, heart failure and has a growing impact on diagnosis, clinical management, and decision making. Through its ability to characterize the myocardium by using multiple different imaging parameters, it provides insight into the etiology of the underlying heart failure and its prognosis. CMR is widely accepted as the reference standard for quantifying chamber size and ejection fraction. Additionally, tissue characterization techniques such as late gadolinium enhancement (LGE) and other quantitative parameters such as T(1) mapping, both native and with measurement of extracellular volume fraction; T(2) mapping; and T(2)* mapping have been validated against histological findings in a wide range of clinical scenarios. In particular, the pattern of LGE in the myocardium can help determine the underlying etiology of the heart failure. The presence and extent of LGE determine prognosis in many of the nonischemic cardiomyopathies. The use of CMR should increase as its utility in characterization and assessment of prognosis in cardiomyopathies is increasingly recognized. CI - Copyright (c) 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. FAU - Patel, Amit R AU - Patel AR AD - Department of Medicine and Radiology, University of Chicago, Chicago, Illinois. FAU - Kramer, Christopher M AU - Kramer CM AD - Departments of Medicine and Radiology and the Cardiovascular Imaging Center, University of Virginia Health System, Charlottesville, Virginia. Electronic address: ckramer@virginia.edu. LA - eng GR - U01 HL117006/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Review PL - United States TA - JACC Cardiovasc Imaging JT - JACC. Cardiovascular imaging JID - 101467978 RN - 0 (Contrast Media) SB - IM MH - Amyloidosis/diagnostic imaging MH - Cardiomyopathies/*diagnostic imaging/genetics/therapy MH - Cardiomyopathy, Dilated/diagnostic imaging MH - Cardiomyopathy, Hypertrophic/diagnostic imaging MH - Contrast Media/administration & dosage MH - Genetic Predisposition to Disease MH - Hemosiderosis/diagnostic imaging MH - Humans MH - Image Interpretation, Computer-Assisted MH - *Magnetic Resonance Imaging MH - Predictive Value of Tests MH - Prognosis MH - Risk Factors MH - Sarcoidosis/diagnostic imaging MH - Severity of Illness Index PMC - PMC5708889 MID - NIHMS900410 OTO - NOTNLM OT - amyloidosis OT - cardiomyopathy OT - cardiovascular magnetic resonance OT - heart failure OT - hypertrophic cardiomyopathy OT - sarcoidosis EDAT- 2017/10/07 06:00 MHDA- 2018/06/12 06:00 PMCR- 2018/10/01 CRDT- 2017/10/07 06:00 PHST- 2017/04/27 00:00 [received] PHST- 2017/08/04 00:00 [revised] PHST- 2017/08/10 00:00 [accepted] PHST- 2017/10/07 06:00 [entrez] PHST- 2017/10/07 06:00 [pubmed] PHST- 2018/06/12 06:00 [medline] PHST- 2018/10/01 00:00 [pmc-release] AID - S1936-878X(17)30776-3 [pii] AID - 10.1016/j.jcmg.2017.08.005 [doi] PST - ppublish SO - JACC Cardiovasc Imaging. 2017 Oct;10(10 Pt A):1180-1193. doi: 10.1016/j.jcmg.2017.08.005.