PMID- 28988099
OWN - NLM
STAT- MEDLINE
DCOM- 20180822
LR  - 20180822
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 615
DP  - 2018 Feb 15
TI  - Chlorinated persistent organic pollutants in serum of New Zealand adults, 
      2011-2013.
PG  - 624-631
LID - S0048-9697(17)32682-7 [pii]
LID - 10.1016/j.scitotenv.2017.09.331 [doi]
AB  - A national survey was conducted in 2011-2013 to assess serum concentrations of 
      persistent organic pollutants (POPs) in adult New Zealanders. Participants were 
      randomly selected from the 2010 Electoral Roll within 64 demographic strata 
      according to 4 age groups, 4 regions, 2 ethnic groups (Maori/non-Maori) and 
      gender. Eligible subjects (n=734) donated up to 30ml of blood, after which serum 
      was pooled (n=49) according to demographic strata prior to analysis by GC-HRMS. 
      Associations between demographic variables (age, region, ethnicity, gender) and 
      serum POPs were assessed using linear regression. The weighted geometric mean 
      (GM) of PCDD/Fs was 5.3pg/g lipid toxic equivalents using the WHO 2005 toxic 
      equivalence factors (TEQ(05)), which increased by age (3.2, 4.4, 4.8, and 8.1pg/g 
      lipid for the 19-24, 25-34, 35-49, and 50-64year age groups, respectively). The 
      weighted GM of dioxin-like PCBs was 1.4pg TEQ(05)/g lipid which also increased by 
      age (0.82, 0.86, 1.4, and 2.3pg/g lipid for the same age groups, respectively). 
      Of the detected OCPs, the highest concentration was observed for p,p'-DDE 
      (weighted GM, 220ng/g lipid) followed by hexachlorobenzene (HCB; 7.3ng/g lipid), 
      beta-HCH (7.0ng/g lipid), and dieldrin (4.7ng/g lipid). For most Cl-POPs, 
      concentrations were lowest in the youngest age group, and were similar for men 
      and women and Maori and non-Maori. Serum Cl-POPs were, on average, 50% lower than 
      those measured 15years earlier in 1997. This survey provides evidence of 
      declining serum concentrations of chlorinated POPs in the New Zealand adult 
      population. Age was the most important determinant of POPs concentrations. Body 
      burdens of PCDD/Fs and PCBs in New Zealand are relatively low by international 
      comparison, while for OCPs they are similar or lower compared to those reported 
      for other developed countries.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Coakley, J
AU  - Coakley J
AD  - Centre for Public Health Research, Massey University, 6021 Wellington, New 
      Zealand. Electronic address: j.d.coakley@massey.ac.nz.
FAU - Bridgen, P
AU  - Bridgen P
AD  - AsureQuality Ltd., 5010 Lower Hutt, New Zealand.
FAU - Bates, M N
AU  - Bates MN
AD  - School of Public Health, University of California, Berkeley, CA 94720-7360, USA.
FAU - Douwes, J
AU  - Douwes J
AD  - Centre for Public Health Research, Massey University, 6021 Wellington, New 
      Zealand.
FAU - 't Mannetje, A
AU  - 't Mannetje A
AD  - Centre for Public Health Research, Massey University, 6021 Wellington, New 
      Zealand.
LA  - eng
PT  - Journal Article
DEP - 20171006
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Adult
MH  - Dichlorodiphenyl Dichloroethylene/blood
MH  - *Environmental Monitoring
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Humans
MH  - Hydrocarbons, Chlorinated/blood
MH  - Male
MH  - Middle Aged
MH  - New Zealand
MH  - Pesticides/blood
MH  - Polychlorinated Biphenyls/blood
MH  - Polychlorinated Dibenzodioxins/blood
MH  - Young Adult
OTO - NOTNLM
OT  - Biological monitoring
OT  - Chlorinated persistent organic pollutants
OT  - Dioxins
OT  - Furans
OT  - Organochlorine pesticides
OT  - Polychlorinated biphenyls
EDAT- 2017/10/11 06:00
MHDA- 2018/08/23 06:00
CRDT- 2017/10/09 06:00
PHST- 2017/07/13 00:00 [received]
PHST- 2017/09/29 00:00 [revised]
PHST- 2017/09/30 00:00 [accepted]
PHST- 2017/10/11 06:00 [pubmed]
PHST- 2018/08/23 06:00 [medline]
PHST- 2017/10/09 06:00 [entrez]
AID - S0048-9697(17)32682-7 [pii]
AID - 10.1016/j.scitotenv.2017.09.331 [doi]
PST - ppublish
SO  - Sci Total Environ. 2018 Feb 15;615:624-631. doi: 10.1016/j.scitotenv.2017.09.331. 
      Epub 2017 Oct 6.