PMID- 28988633
OWN - NLM
STAT- MEDLINE
DCOM- 20190308
LR  - 20190806
IS  - 1878-4372 (Electronic)
IS  - 1360-1385 (Linking)
VI  - 22
IP  - 12
DP  - 2017 Dec
TI  - Stabilizing the Transcription Factors by E3 Ligase COP1.
PG  - 999-1001
LID - S1360-1385(17)30211-X [pii]
LID - 10.1016/j.tplants.2017.09.012 [doi]
AB  - Photomorphogenesis is oppositely regulated by two groups of transcription 
      factors. CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) degrades the positive factors but 
      stabilizes the negative ones to predominantly repress photomorphogenesis. It is 
      known that COP1 degrades substrates as an E3 ligase. Two recent studies unraveled 
      the long-sought mechanisms of how COP1 stabilizes the negative transcription 
      factors.
CI  - Copyright (c) 2017 Elsevier Ltd. All rights reserved.
FAU - Pan, Ying
AU  - Pan Y
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China.
FAU - Shi, Hui
AU  - Shi H
AD  - College of Life Sciences, Capital Normal University, Beijing 100048, China. 
      Electronic address: hui.shi@cnu.edu.cn.
LA  - eng
PT  - Comment
PT  - Journal Article
DEP - 20171004
PL  - England
TA  - Trends Plant Sci
JT  - Trends in plant science
JID - 9890299
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Basic Helix-Loop-Helix Transcription Factors)
RN  - 0 (PIF3 protein, Arabidopsis)
RN  - 0 (Transcription Factors)
RN  - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis)
RN  - EC 2.3.2.27 (Ubiquitin-Protein Ligases)
RN  - EC 2.7.- (Protein Kinases)
RN  - EC 2.7.1.- (BIN2 protein, Arabidopsis)
SB  - IM
CON - Curr Biol. 2016 Jan 25;26(2):139-149. PMID: 26748855
CON - Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3539-3544. PMID: 28292892
MH  - *Arabidopsis
MH  - Arabidopsis Proteins/genetics
MH  - Basic Helix-Loop-Helix Transcription Factors
MH  - Darkness
MH  - Gene Expression Regulation, Plant
MH  - Phosphorylation
MH  - Protein Kinases
MH  - Transcription Factors
MH  - Ubiquitin-Protein Ligases/*genetics
OTO - NOTNLM
OT  - BIN2
OT  - COP1
OT  - EBF1/EBF2
OT  - EIN3
OT  - PIF3
OT  - photomorphogenesis
EDAT- 2017/10/11 06:00
MHDA- 2019/03/09 06:00
CRDT- 2017/10/10 06:00
PHST- 2017/08/26 00:00 [received]
PHST- 2017/09/22 00:00 [revised]
PHST- 2017/09/22 00:00 [accepted]
PHST- 2017/10/11 06:00 [pubmed]
PHST- 2019/03/09 06:00 [medline]
PHST- 2017/10/10 06:00 [entrez]
AID - S1360-1385(17)30211-X [pii]
AID - 10.1016/j.tplants.2017.09.012 [doi]
PST - ppublish
SO  - Trends Plant Sci. 2017 Dec;22(12):999-1001. doi: 10.1016/j.tplants.2017.09.012. 
      Epub 2017 Oct 4.