PMID- 28988878 OWN - NLM STAT- MEDLINE DCOM- 20180831 LR - 20220410 IS - 1436-2023 (Electronic) IS - 0949-2658 (Linking) VI - 23 IP - 1 DP - 2018 Jan TI - Age variation in the minimum clinically important difference in SRS-22r after surgical treatment for adult spinal deformity - A single institution analysis in Japan. PG - 20-25 LID - S0949-2658(17)30246-4 [pii] LID - 10.1016/j.jos.2017.09.015 [doi] AB - BACKGROUND: The Scoliosis Research Society-22r (SRS-22r) has been shown to be reliable, valid and responsive to change in patients with adult spinal deformity (ASD) undergoing surgery. The minimum clinically important difference (MCID) quantifies a threshold value of improvement that is clinically relevant to the patient. Health-related quality of life scores depend on age. The purpose of this study was to assess MCID threshold values stratified by age for SRS-22r domains in patients with ASD undergoing surgical correction. METHODS: We identified a consecutive series of 184 Japanese ASD patients who completed the SRS-22r and Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) preoperatively and 1 year postoperatively. Effectiveness as measured on the JOABPEQ was used as the anchor to determine MCID for the Function, Pain, and Mental health domains using receiver-operating-characteristic (ROC) curve analysis. We performed MCID analysis stratified by age (<70 or >/=70). RESULTS: Mean preoperative SRS-22r Function score was 2.69 improving to 3.23 at postoperatively (p < 0.001). Mean preoperative SRS-22r Pain score was 3.04 improving to 3.78 at postoperatively (p < 0.001). Mean preoperative SRS-22r Mental health score was 2.72 improving to 3.25 at postoperatively (p < 0.001). There was a statistically difference in change in domain score between "not effective" and "effective" (p < 0.001). The ROC curve analysis methods yielded MCID values of 0.58 for Function, 0.55 for Pain, and 0.70 for Mental health domains. There was difference of MCID value for Function and Mental health domain between aged <70 and >/=70; 0.78 and 0.55 for Function; 0.70 and 0.48 for Mental health. CONCLUSION: Results of this study showed that MCID threshold values for SRS-22 Function and Mental health domains in older than 70 was lower than in younger than 70, potentially implying that older patients have lower expectation. CI - Copyright (c) 2017 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved. FAU - Arima, Hideyuki AU - Arima H AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan; Norton Leatherman Spine Center, Louisville, 40202 KY, USA; Department of Orthopedic Surgery, University of Louisville School of Medicine, Louisville, 40202 KY, USA. Electronic address: arihidee@yahoo.co.jp. FAU - Carreon, Leah Y AU - Carreon LY AD - Norton Leatherman Spine Center, Louisville, 40202 KY, USA. FAU - Glassman, Steven D AU - Glassman SD AD - Norton Leatherman Spine Center, Louisville, 40202 KY, USA; Department of Orthopedic Surgery, University of Louisville School of Medicine, Louisville, 40202 KY, USA. FAU - Yamato, Yu AU - Yamato Y AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Hasegawa, Tomohiko AU - Hasegawa T AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Togawa, Daisuke AU - Togawa D AD - Division of Geriatric Musculoskeletal Health, Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Kobayashi, Sho AU - Kobayashi S AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Yoshida, Go AU - Yoshida G AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Yasuda, Tatsuya AU - Yasuda T AD - Department of Orthopaedic Surgery, Hamamatsu Medical Center, Hamamatsu, Shizuoka, Japan. FAU - Banno, Tomohiro AU - Banno T AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Oe, Shin AU - Oe S AD - Division of Geriatric Musculoskeletal Health, Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Mihara, Yuki AU - Mihara Y AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. FAU - Matsuyama, Yukihiro AU - Matsuyama Y AD - Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192 Shizuoka, Japan. LA - eng PT - Evaluation Study PT - Journal Article DEP - 20171006 PL - Japan TA - J Orthop Sci JT - Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association JID - 9604934 SB - IM MH - Academic Medical Centers MH - Adult MH - Age Factors MH - Aged MH - Cohort Studies MH - Databases, Factual MH - Female MH - Follow-Up Studies MH - Humans MH - Japan MH - Male MH - Middle Aged MH - Pain Measurement MH - *Patient Reported Outcome Measures MH - *Quality of Life MH - ROC Curve MH - Range of Motion, Articular/physiology MH - Retrospective Studies MH - Risk Assessment MH - Scoliosis/*diagnosis/*surgery MH - Severity of Illness Index MH - Sex Factors MH - Spinal Fusion/instrumentation/*methods MH - Statistics, Nonparametric MH - Surveys and Questionnaires MH - Treatment Outcome EDAT- 2017/10/11 06:00 MHDA- 2018/09/01 06:00 CRDT- 2017/10/10 06:00 PHST- 2017/03/11 00:00 [received] PHST- 2017/08/25 00:00 [revised] PHST- 2017/09/17 00:00 [accepted] PHST- 2017/10/11 06:00 [pubmed] PHST- 2018/09/01 06:00 [medline] PHST- 2017/10/10 06:00 [entrez] AID - S0949-2658(17)30246-4 [pii] AID - 10.1016/j.jos.2017.09.015 [doi] PST - ppublish SO - J Orthop Sci. 2018 Jan;23(1):20-25. doi: 10.1016/j.jos.2017.09.015. Epub 2017 Oct 6.