PMID- 28991770 OWN - NLM STAT- MEDLINE DCOM- 20190701 LR - 20191210 IS - 1857-9345 (Print) IS - 1857-9345 (Linking) VI - 38 IP - 2 DP - 2017 Sep 1 TI - Transition Towards Transradial Approach Improves Outcomes of Acute Myocardial Infarction PCI. PG - 69-78 LID - /j/prilozi.2017.38.issue-2/prilozi-2017-0024/prilozi-2017-0024.xml [pii] LID - 10.1515/prilozi-2017-0024 [doi] AB - INTRODUCTION AND AIM: Transradial (TRA) instead of transfemoral (TFA) approach strategy has been presented in research literature as superior access strategy especially for acute ST elevation myocardial infarction (STEMI) primary percutaneous coronary intervention (PCI). There is a paucity of registry-based data of outcomes from default TRA strategy compared to TFA. MATERIALS AND METHODS: All-comers STEMI PCI institutional Registry identified 1808 consecutive patients in time-frame of 40 months from 2007 to 2010, without making any exclusions. Moreover, we applied Propensity Score Matching (PSM) to replace randomization, address the potential confounding and selection bias. PSM derived 565 congruent pairs of patients from the groups. RESULTS: After 30 days the primary composite endpoint of major adverse cardiovascular events (MACE) was in favor of TRA 6.5% vs. 12.4% in TFA group, simultaneously secondary endpoints of death in TRA with rate of 4.8% and with rate of 10.1% in TFA. Moreover, the rate of major access related bleeding was 1.1% in TRA vs. 8.5% in TFA, in contrast the major non-access related bleeding was 1.8% and 2.4% respectively showed no significant difference. One year Kaplan Meier survival plots were in favor of TRA. CONCLUSIONS: Default transradial access strategy is associated with improved STEMI PCI outcomes. FAU - Kalpak, Oliver AU - Kalpak O AD - . FAU - Donev, Donco AU - Donev D AD - . FAU - Pejkov, Hristo AU - Pejkov H AD - . FAU - Antov, Slobodan AU - Antov S AD - . FAU - Kalpak, Gjorgji AU - Kalpak G AD - . FAU - Kedev, Sasko AU - Kedev S AD - . LA - eng PT - Journal Article PL - North Macedonia TA - Pril (Makedon Akad Nauk Umet Odd Med Nauki) JT - Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) JID - 101677081 SB - IM MH - Aged MH - Catheterization, Peripheral/adverse effects/mortality/*trends MH - Clinical Decision-Making MH - Female MH - *Femoral Artery MH - Humans MH - Male MH - Middle Aged MH - Percutaneous Coronary Intervention/adverse effects/mortality/*trends MH - Practice Patterns, Physicians'/*trends MH - Punctures MH - *Radial Artery MH - Registries MH - Republic of North Macedonia MH - Risk Assessment MH - Risk Factors MH - ST Elevation Myocardial Infarction/diagnosis/mortality/*surgery MH - Time Factors MH - Treatment Outcome OTO - NOTNLM OT - STEMI OT - TFA OT - TRA OT - acute myocardial infarction PCI OT - outcomes EDAT- 2017/10/11 06:00 MHDA- 2019/07/02 06:00 CRDT- 2017/10/10 06:00 PHST- 2017/10/10 06:00 [entrez] PHST- 2017/10/11 06:00 [pubmed] PHST- 2019/07/02 06:00 [medline] AID - /j/prilozi.2017.38.issue-2/prilozi-2017-0024/prilozi-2017-0024.xml [pii] AID - 10.1515/prilozi-2017-0024 [doi] PST - ppublish SO - Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017 Sep 1;38(2):69-78. doi: 10.1515/prilozi-2017-0024.