PMID- 29020525 OWN - NLM STAT- MEDLINE DCOM- 20180724 LR - 20181113 IS - 1541-2563 (Electronic) IS - 1541-2555 (Print) IS - 1541-2563 (Linking) VI - 14 IP - 6 DP - 2017 Dec TI - Social Determinants of Adherence to Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease. PG - 610-617 LID - 10.1080/15412555.2017.1379070 [doi] AB - Adherence to pulmonary rehabilitation (PR) is low. Previous studies have focused on clinical predictors of PR completion. We aimed to identify social determinants of adherence to PR. A cross-sectional analysis of a database of COPD patients (N = 455) in an outpatient PR program was performed. Adherence, a ratio of attended-to-prescribed sessions, was coded as low (<35%), moderate (35-85%), and high (>85%). Individual-level measures included age, sex, race, BMI, smoking status, pack-years, baseline 6-minute walk distance (6MWD: <150, 150-249, >/=250), co-morbidities, depression, and prescribed PR sessions (30). Fifteen area-level measures aggregated to Census tracts were obtained from the U.S. Census after geocoding patients' addresses. Using exploratory factor analysis, a neighborhood socioeconomic disadvantage index was constructed, which included variables with factor loading >0.5: poverty, public assistance, households without vehicles, cost burden, unemployment, and minority population. Multivariate regression models were adjusted for clustering on Census tracts. Twenty-six percent of patients had low adherence, 23% were moderately adherent, 51% were highly adherent. In the best fitted full model, each decile increase in neighborhood socioeconomic disadvantage increased the risk of moderate vs high adherence by 14% (p < 0.01). Smoking tripled the relative risk of low adherence (p < 0.01), while each increase in 6MWD category decreased that risk by 72% (p < 0.01) and 84% (p < 0.001), respectively. These findings show that, relative to high adherence, low adherence is associated with limited functional capacity and current smoking, while moderate adherence is associated with socioeconomic disadvantage. The distinction highlights different pathways to suboptimal adherence and calls for tailored intervention approaches. FAU - Oates, Gabriela R AU - Oates GR AUID- ORCID: 0000-0003-4052-1524 AD - a Preventive Medicine , University of Alabama at Birmingham , Birmingham , AL , USA. FAU - Hamby, Bryant W AU - Hamby BW AD - b Sociology , University of Alabama at Birmingham , Birmingham , AL , USA. FAU - Stepanikova, Irena AU - Stepanikova I AD - b Sociology , University of Alabama at Birmingham , Birmingham , AL , USA. FAU - Knight, Sara J AU - Knight SJ AD - a Preventive Medicine , University of Alabama at Birmingham , Birmingham , AL , USA. AD - c Birmingham Veterans Affairs Medical Center , Birmingham , AL , USA. FAU - Bhatt, Surya P AU - Bhatt SP AD - d Lung Health Center and Pulmonary, Allergy and Critical Care Medicine , University of Alabama at Birmingham , Birmingham , AL , USA. FAU - Hitchcock, Jason AU - Hitchcock J AD - e Cardiopulmonary Rehabilitation , University of Alabama at Birmingham , Birmingham , AL , USA. FAU - Schumann, Christopher AU - Schumann C AD - e Cardiopulmonary Rehabilitation , University of Alabama at Birmingham , Birmingham , AL , USA. FAU - Dransfield, Mark T AU - Dransfield MT AD - c Birmingham Veterans Affairs Medical Center , Birmingham , AL , USA. AD - d Lung Health Center and Pulmonary, Allergy and Critical Care Medicine , University of Alabama at Birmingham , Birmingham , AL , USA. LA - eng GR - K12 HS023009/HS/AHRQ HHS/United States PT - Journal Article DEP - 20171011 PL - England TA - COPD JT - COPD JID - 101211769 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Comorbidity MH - Cost of Illness MH - Cross-Sectional Studies MH - Depression/psychology MH - Factor Analysis, Statistical MH - Female MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Minority Groups/*statistics & numerical data MH - Motor Vehicles/statistics & numerical data MH - Multivariate Analysis MH - Patient Compliance/*statistics & numerical data MH - Poverty/*statistics & numerical data MH - Public Assistance/*statistics & numerical data MH - Pulmonary Disease, Chronic Obstructive/epidemiology/psychology/*rehabilitation MH - Residence Characteristics MH - Respiratory Therapy/*statistics & numerical data MH - Smoking/epidemiology MH - *Social Class MH - Social Determinants of Health MH - Unemployment/*statistics & numerical data MH - United States MH - Walk Test PMC - PMC5830088 MID - NIHMS944774 OTO - NOTNLM OT - adherence OT - pulmonary rehabilitation OT - social determinants OT - socioeconomic disadvantage COIS- Declaration of interest: The authors report no conflicts of interest. The content is the responsibility of the authors and does not necessarily represent the official views of the Agency for Healthcare Research and Quality. EDAT- 2017/10/12 06:00 MHDA- 2018/07/25 06:00 PMCR- 2018/02/28 CRDT- 2017/10/12 06:00 PHST- 2017/10/12 06:00 [pubmed] PHST- 2018/07/25 06:00 [medline] PHST- 2017/10/12 06:00 [entrez] PHST- 2018/02/28 00:00 [pmc-release] AID - 10.1080/15412555.2017.1379070 [doi] PST - ppublish SO - COPD. 2017 Dec;14(6):610-617. doi: 10.1080/15412555.2017.1379070. Epub 2017 Oct 11.