PMID- 29022093 OWN - NLM STAT- MEDLINE DCOM- 20181113 LR - 20181113 IS - 1433-0423 (Electronic) IS - 0941-293X (Linking) VI - 114 IP - 11 DP - 2017 Nov TI - [Seasonal allergic conjunctivitis]. PG - 1053-1065 LID - 10.1007/s00347-017-0580-1 [doi] AB - Seasonal allergic conjunctivitis (SAC) is a frequent disease, which is often associated with allergic rhinitis and subsequently manifested as allergic rhinoconjunctivitis. In contrast to other types of chronic allergic conjunctivitis, the course of SAC is not sight-threatening. Pathogenetically, the underlying cause of SAC is an immunoglobulin E (IgE) mediated, Th2-driven type 1 hypersensitivity reaction. Clinically it presents with itching, light-red conjunctival injection as well as chemosis that exceeds the extent of conjunctival injection. The goals of treatment are relief of acute signs and symptoms, control of the underlying inflammatory process and utilization of preventive options. Dually effective local therapeutics combine the advantages of rapid action with a relatively long-lasting effect by a two-fold active approach. Specific immunotherapy is useful in selected patients. FAU - Schroder, K AU - Schroder K AD - Klinik fur Augenheilkunde, Universitatsklinikum Dusseldorf, Medizinische Fakultat, Heinrich-Heine-Universitat Dusseldorf, Moorenstr. 5, 40225, Dusseldorf, Deutschland. katharina.schroeder@med.uni-duesseldorf.de. FAU - Finis, D AU - Finis D AD - Klinik fur Augenheilkunde, Universitatsklinikum Dusseldorf, Medizinische Fakultat, Heinrich-Heine-Universitat Dusseldorf, Moorenstr. 5, 40225, Dusseldorf, Deutschland. FAU - Meller, S AU - Meller S AD - Hautklinik, Universitatsklinikum Dusseldorf, Dusseldorf, Deutschland. FAU - Wagenmann, M AU - Wagenmann M AD - HNO-Klinik, Universitatsklinikum Dusseldorf, Dusseldorf, Deutschland. FAU - Geerling, G AU - Geerling G AD - Klinik fur Augenheilkunde, Universitatsklinikum Dusseldorf, Medizinische Fakultat, Heinrich-Heine-Universitat Dusseldorf, Moorenstr. 5, 40225, Dusseldorf, Deutschland. FAU - Pleyer, U AU - Pleyer U AD - Universitats-Augenklinik, Charite - Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland. uwe.pleyer@charite.de. LA - ger PT - Journal Article PT - Review TT - Saisonale allergische Konjunktivitis. PL - Germany TA - Ophthalmologe JT - Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft JID - 9206148 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Conjunctivitis, Allergic/*diagnosis/immunology/therapy MH - Diagnosis, Differential MH - Humans MH - Immunoglobulin E/blood MH - Immunotherapy MH - Th2 Cells/immunology OTO - NOTNLM OT - Acute allergic conjunctivitis OT - Diagnostics OT - Immunotherapy OT - Local therapeutics OT - Rhinoconjunctivitis EDAT- 2017/10/13 06:00 MHDA- 2018/11/14 06:00 CRDT- 2017/10/13 06:00 PHST- 2017/10/13 06:00 [pubmed] PHST- 2018/11/14 06:00 [medline] PHST- 2017/10/13 06:00 [entrez] AID - 10.1007/s00347-017-0580-1 [pii] AID - 10.1007/s00347-017-0580-1 [doi] PST - ppublish SO - Ophthalmologe. 2017 Nov;114(11):1053-1065. doi: 10.1007/s00347-017-0580-1.