PMID- 29024757
OWN - NLM
STAT- MEDLINE
DCOM- 20190204
LR  - 20190215
IS  - 2241-5955 (Electronic)
IS  - 1109-9666 (Linking)
VI  - 59
IP  - 3
DP  - 2018 May-Jun
TI  - A meta-analysis on the correlation between admission hyperglycemia and myocardial 
      infarct size on CMRI.
PG  - 174-178
LID - S1109-9666(17)30228-2 [pii]
LID - 10.1016/j.hjc.2017.09.009 [doi]
AB  - AIMS: The aim was to compare the size of the myocardial infarct detected on 
      cardiovascular magnetic resonance imaging (CMR) between patients with and without 
      admission hyperglycemia after acute myocardial infarction (AMI). METHODS: Studies 
      were identified by searching on MEDLINE, EMBASE, and CINAHL databases. A 
      systematic review was conducted by two independent reviewers. Microvascular 
      obstruction (MVO) and late gadolinium enhancement (LGE) were pooled from 
      available studies to calculate the standardized mean difference (SMD) in post-MI 
      infarct size between patients with and without hyperglycemia at admission. 
      RESULTS: The systematic review yielded 5 studies with MCR data for patients with 
      and without admission hyperglycemia. The total number of patients included in 
      this study was 911. A statistically significant difference was detected in MVO 
      between patients with and without admission hyperglycemia (SMD = 0.79, 95% CI: 
      0.11, 1.47, P < 0.00001). The difference in LGE between patients with and without 
      admission hyperglycemia was also significant (SMD = 0.57, 95% CI: -0.04, 1.18, 
      P < 0.00001). CONCLUSION: The main finding of our analyses is that the size of 
      myocardial infarct detected on CMR is positively correlated to admission 
      hyperglycemia in patients with AMI. The clinical importance of this study lies in 
      the accurate assessment of prognostic value of admission glucose, which would 
      help clinicians in risk stratification and treatment decision-making.
CI  - Copyright (c) 2017 Hellenic Society of Cardiology. Published by Elsevier B.V. All 
      rights reserved.
FAU - Pak, Stella
AU  - Pak S
AD  - Department of Medicine, Kettering Medical Center, Kettering, OH, 45429, USA. 
      Electronic address: Stella.Pak@rockets.utoledo.edu.
FAU - Yatsynovich, Yan
AU  - Yatsynovich Y
AD  - Department of Medicine, Kettering Medical Center, Kettering, OH, 45429, USA.
FAU - Markovic, John-Phillip
AU  - Markovic JP
AD  - Department of Medicine, Kettering Medical Center, Kettering, OH, 45429, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
DEP - 20171010
PL  - Netherlands
TA  - Hellenic J Cardiol
JT  - Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese
JID - 101257381
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Blood Glucose/*analysis
MH  - Diagnostic Tests, Routine/methods
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine
MH  - *Myocardial Infarction/blood/diagnosis
MH  - Prognosis
MH  - Risk Assessment
MH  - Severity of Illness Index
OTO - NOTNLM
OT  - Cardiovascular Magnetic Resonance Imaging
OT  - Dysglycemia
OT  - Hyperglycemia
OT  - Myocardial Infarction
EDAT- 2017/10/13 06:00
MHDA- 2019/02/05 06:00
CRDT- 2017/10/13 06:00
PHST- 2017/05/07 00:00 [received]
PHST- 2017/09/07 00:00 [revised]
PHST- 2017/09/19 00:00 [accepted]
PHST- 2017/10/13 06:00 [pubmed]
PHST- 2019/02/05 06:00 [medline]
PHST- 2017/10/13 06:00 [entrez]
AID - S1109-9666(17)30228-2 [pii]
AID - 10.1016/j.hjc.2017.09.009 [doi]
PST - ppublish
SO  - Hellenic J Cardiol. 2018 May-Jun;59(3):174-178. doi: 10.1016/j.hjc.2017.09.009. 
      Epub 2017 Oct 10.