PMID- 29025419
OWN - NLM
STAT- MEDLINE
DCOM- 20180207
LR  - 20181202
IS  - 1471-2334 (Electronic)
IS  - 1471-2334 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Oct 12
TI  - Strong associations between national prevalence of various STIs suggests sexual 
      network connectivity is a common underpinning risk factor.
PG  - 682
LID - 10.1186/s12879-017-2794-x [doi]
LID - 682
AB  - BACKGROUND: If national peak Human Immunodeficiency Virus (HIV) prevalence is 
      positively associated with the prevalence of other sexually transmitted 
      infections (STIs) from before or early on in the HIV epidemics this would suggest 
      common underlying drivers. METHODS: Pearson's correlations were calculated 
      between the prevalence of seven STIs at a country-level: chlamydia, gonorrhoea, 
      trichomoniasis, syphilis, bacterial vaginosis, herpes simplex virus-2 (HSV-2) and 
      HIV. RESULTS: The prevalence of all the STIs was highest in the sub-Saharan 
      African region excluding chlamydia. The prevalence of all seven STIs were 
      positively correlated excluding chlamydia. The correlations were strongest for 
      HIV-HSV-2 (r = 0.85, P < 0.0001) and HSV-2-trichomoniasis (r = 0.82, P < 0.0001). 
      CONCLUSION: Our results of a generally positive association between the 
      prevalences of a range of STIs suggests that higher prevalences were driven by 
      common underlying determinants. We review different types of evidence which 
      suggest that differential sexual connectivity is a plausible common determinant.
FAU - Kenyon, Chris
AU  - Kenyon C
AUID- ORCID: 0000-0002-2557-8998
AD  - Sexually Transmitted Infections HIV/STI Unit, Institute of Tropical Medicine, 
      Antwerp, Belgium. ckenyon@itg.be.
AD  - Division of Infectious Diseases and HIV Medicine, University of Cape Town, Anzio 
      Road, Observatory, 7700, South Africa. ckenyon@itg.be.
LA  - eng
PT  - Journal Article
DEP - 20171012
PL  - England
TA  - BMC Infect Dis
JT  - BMC infectious diseases
JID - 100968551
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Epidemics
MH  - Female
MH  - Gonorrhea/epidemiology
MH  - HIV Infections/*epidemiology
MH  - Herpesvirus 2, Human
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
MH  - Sexual Behavior
MH  - Sexually Transmitted Diseases/*epidemiology
MH  - Social Networking
MH  - Syphilis/epidemiology
MH  - Trichomonas Infections/epidemiology
MH  - Vaginosis, Bacterial/epidemiology
MH  - Young Adult
PMC - PMC5639489
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The research involved secondary data 
      analysis of STI prevalence estimates. No specific ethics committee approval was 
      therefore necessary for this study. CONSENT FOR PUBLICATION: Not applicable. 
      COMPETING INTERESTS: The author declares he has no competing interests. 
      PUBLISHER'S NOTE: Springer Nature remains neutral with regard to jurisdictional 
      claims in published maps and institutional affiliations.
EDAT- 2017/10/14 06:00
MHDA- 2018/02/08 06:00
PMCR- 2017/10/12
CRDT- 2017/10/14 06:00
PHST- 2017/05/30 00:00 [received]
PHST- 2017/10/04 00:00 [accepted]
PHST- 2017/10/14 06:00 [entrez]
PHST- 2017/10/14 06:00 [pubmed]
PHST- 2018/02/08 06:00 [medline]
PHST- 2017/10/12 00:00 [pmc-release]
AID - 10.1186/s12879-017-2794-x [pii]
AID - 2794 [pii]
AID - 10.1186/s12879-017-2794-x [doi]
PST - epublish
SO  - BMC Infect Dis. 2017 Oct 12;17(1):682. doi: 10.1186/s12879-017-2794-x.