PMID- 29026592
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2050-6406 (Print)
IS  - 2050-6414 (Electronic)
IS  - 2050-6406 (Linking)
VI  - 5
IP  - 6
DP  - 2017 Oct
TI  - Yield of prolonged wireless pH monitoring in achalasia patients successfully 
      treated with pneumatic dilation.
PG  - 789-795
LID - 10.1177/2050640616681366 [doi]
AB  - BACKGROUND: Gastro-oesophageal reflux disease (GORD) is a long-term complication 
      of achalasia treatments. The aim of our study was to evaluate the yield of 
      prolonged wireless pH monitoring in patients with successfully treated achalasia 
      and its influence on proton pump inhibitor (PPI) use. METHODS: Twenty-five 
      patients with achalasia who underwent prolonged wireless pH monitoring after a 
      successful treatment with pneumatic dilation were enrolled. pH variables were 
      analysed in the first 24 hours of monitoring to determine if tracings were 
      indicative of GORD; the same variables were analysed in the following 24-hour 
      period in order to obtain a worst-day diagnosis of GORD. PPI therapy before and 
      after the test was recorded. RESULTS: Five out of 25 patients had GORD diagnosis 
      during the first day of monitoring and four of them had oesophagitis at 
      endoscopy. During the following days of monitoring four more patients had a 
      diagnosis of GORD. Out of the 25 patients, PPIs were started after the test in 
      six asymptomatic GORD-positive ones, whereas prescription of PPIs was stopped 
      without detrimental effect on symptoms in three GORD-negative patients. 
      CONCLUSIONS: Prolonged wireless pH monitoring is a useful test to be added to 
      endoscopy in order to evaluate GORD and to optimise antisecretory treatment in 
      successfully treated achalasia patients.
FAU - Mauro, Aurelio
AU  - Mauro A
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
FAU - Franchina, Marianna
AU  - Franchina M
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
FAU - Elvevi, Alessandra
AU  - Elvevi A
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
FAU - Pugliese, Delia
AU  - Pugliese D
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
FAU - Tenca, Andrea
AU  - Tenca A
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
AD  - Department of Gastroenterology, Helsinki University Hospital, University of 
      Helsinki, Finland.
FAU - Conte, Dario
AU  - Conte D
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
FAU - Penagini, Roberto
AU  - Penagini R
AD  - Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca Granda Ospedale Maggiore 
      Policlinico; Department of Pathophysiology and Transplantation - Universita degli 
      Studi di Milano, Italy.
LA  - eng
PT  - Journal Article
DEP - 20161122
PL  - England
TA  - United European Gastroenterol J
JT  - United European gastroenterology journal
JID - 101606807
PMC - PMC5625868
OTO - NOTNLM
OT  - Prolonged wireless pH monitoring
OT  - achalasia
OT  - gastro-oesophageal reflux disease
OT  - oesophagus
OT  - pH-metry
EDAT- 2017/10/14 06:00
MHDA- 2017/10/14 06:01
PMCR- 2017/10/01
CRDT- 2017/10/14 06:00
PHST- 2016/08/25 00:00 [received]
PHST- 2016/11/06 00:00 [accepted]
PHST- 2017/10/14 06:00 [entrez]
PHST- 2017/10/14 06:00 [pubmed]
PHST- 2017/10/14 06:01 [medline]
PHST- 2017/10/01 00:00 [pmc-release]
AID - 10.1177_2050640616681366 [pii]
AID - 10.1177/2050640616681366 [doi]
PST - ppublish
SO  - United European Gastroenterol J. 2017 Oct;5(6):789-795. doi: 
      10.1177/2050640616681366. Epub 2016 Nov 22.