PMID- 29027289 OWN - NLM STAT- MEDLINE DCOM- 20171019 LR - 20181113 IS - 1365-2613 (Electronic) IS - 0959-9673 (Print) IS - 0959-9673 (Linking) VI - 98 IP - 4 DP - 2017 Aug TI - Polychlorinated dibenzo-p-dioxins and dibenzofurans levels in piglet liver with various diseases. PG - 214-220 LID - 10.1111/iep.12238 [doi] AB - This study deals with the levels of toxic polychlorinated dibenzo-p-dioxin and furan congeners (PCDD/Fs) in the livers of piglets affected by infectious diseases using isotope dilution high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS). Seventeen toxic congeners in the liver samples infected with bacterial and viral diseases were compared. For porcine reproductive and respiratory syndrome virus (PRRSV) samples, the North American- and European-type PRRS diseases were observed. This study shows that there are significantly different levels of PCDD/Fs, present, which vary according to the types of diseases as evidenced by our analysis of the piglet liver samples. CI - (c) 2017 The Authors. International Journal of Experimental Pathology (c) 2017 International Journal of Experimental Pathology. FAU - Shin, Jeoung Hwa AU - Shin JH AD - Seoul Center, Korea Basic Science Institute, Seoul, South Korea. FAU - Ji, Won Hyun AU - Ji WH AD - Institute of Mine Reclamation Technology, Mine Reclamation Corporation, Wonju, South Korea. FAU - Chae, Chanhee AU - Chae C AD - College of Veterinary Medicine, Seoul National University, Seoul, South Korea. FAU - Gorinstein, Shela AU - Gorinstein S AUID- ORCID: 0000-0002-0621-8305 AD - Institute for Drug Research, School of Pharmacy, Hadassah Medical School, The Hebrew University, Jerusalem, Israel. FAU - Ahn, Yun Gyong AU - Ahn YG AUID- ORCID: 0000-0003-4256-3824 AD - Western Seoul Center, Korea Basic Science Institute, Seoul, South Korea. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Int J Exp Pathol JT - International journal of experimental pathology JID - 9014042 RN - 0 (Benzofurans) RN - 0 (Polychlorinated Dibenzodioxins) SB - IM MH - Animals MH - Benzofurans/*pharmacology MH - Chemical and Drug Induced Liver Injury MH - Liver/*drug effects MH - Mass Spectrometry/methods MH - Polychlorinated Dibenzodioxins/*pharmacology MH - Swine PMC - PMC5639352 OTO - NOTNLM OT - bacillus nature diseases OT - piglet OT - polychlorinated dibenzo-p-dioxins/furans OT - porcine reproductive and respiratory syndrome virus (PRRSV) EDAT- 2017/10/14 06:00 MHDA- 2017/10/20 06:00 PMCR- 2018/08/01 CRDT- 2017/10/14 06:00 PHST- 2017/04/07 00:00 [received] PHST- 2017/07/13 00:00 [accepted] PHST- 2017/10/14 06:00 [entrez] PHST- 2017/10/14 06:00 [pubmed] PHST- 2017/10/20 06:00 [medline] PHST- 2018/08/01 00:00 [pmc-release] AID - IEP12238 [pii] AID - 10.1111/iep.12238 [doi] PST - ppublish SO - Int J Exp Pathol. 2017 Aug;98(4):214-220. doi: 10.1111/iep.12238.