PMID- 29029768
OWN - NLM
STAT- MEDLINE
DCOM- 20181015
LR  - 20181015
IS  - 1365-229X (Electronic)
IS  - 0009-9260 (Linking)
VI  - 73
IP  - 2
DP  - 2018 Feb
TI  - Value of 100 kVp scan with sinogram-affirmed iterative reconstruction algorithm 
      on a single-source CT system during whole-body CT for radiation and contrast 
      medium dose reduction: an intra-individual feasibility study.
PG  - 217.e7-217.e16
LID - S0009-9260(17)30465-8 [pii]
LID - 10.1016/j.crad.2017.09.006 [doi]
AB  - AIM: To perform an intra-individual investigation of the usefulness of a contrast 
      medium (CM) and radiation dose-reduction protocol using single-source computed 
      tomography (CT) combined with 100 kVp and sinogram-affirmed iterative 
      reconstruction (SAFIRE) for whole-body CT (WBCT; chest-abdomen-pelvis CT) in 
      oncology patients. MATERIALS AND METHODS: Forty-three oncology patients who had 
      undergone WBCT under both 120 and 100 kVp protocols at different time points 
      (mean interscan intervals: 98 days) were included retrospectively. The CM doses 
      for the 120 and 100 kVp protocols were 600 and 480 mg iodine/kg, respectively; 
      120 kVp images were reconstructed with filtered back-projection (FBP), whereas 
      100 kVp images were reconstructed with FBP (100 kVp-F) and the SAFIRE (100 
      kVp-S). The size-specific dose estimate (SSDE), iodine load and image quality of 
      each protocol were compared. RESULTS: The SSDE and iodine load of 100 kVp 
      protocol were 34% and 21%, respectively, lower than of 120 kVp protocol (SSDE: 
      10.6+/-1.1 versus 16.1+/-1.8 mGy; iodine load: 24.8+/-4versus 31.5+/-5.5 g iodine, 
      p<0.01). Contrast enhancement, objective image noise, contrast-to-noise-ratio, 
      and visual score of 100 kVp-S were similar to or better than of 120 kVp protocol. 
      CONCLUSION: Compared with the 120 kVp protocol, the combined use of 100 kVp and 
      SAFIRE in WBCT for oncology assessment with an SSCT facilitated substantial 
      reduction in the CM and radiation dose while maintaining image quality.
CI  - Copyright (c) 2017 The Royal College of Radiologists. Published by Elsevier Ltd. 
      All rights reserved.
FAU - Nagayama, Y
AU  - Nagayama Y
AD  - Department of Radiology, Kumamoto City Hospital 1-1-60, Koto, Higashi-ku, 
      Kumamoto City, 862-0909, Japan; Department of Diagnostic Radiology, Graduate 
      School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 
      860-8556, Japan. Electronic address: y.nagayama1980@gmail.com.
FAU - Nakaura, T
AU  - Nakaura T
AD  - Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto 
      University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
FAU - Oda, S
AU  - Oda S
AD  - Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto 
      University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
FAU - Tsuji, A
AU  - Tsuji A
AD  - Department of Radiology, Kumamoto City Hospital 1-1-60, Koto, Higashi-ku, 
      Kumamoto City, 862-0909, Japan.
FAU - Urata, J
AU  - Urata J
AD  - Department of Radiology, Kumamoto City Hospital 1-1-60, Koto, Higashi-ku, 
      Kumamoto City, 862-0909, Japan.
FAU - Furusawa, M
AU  - Furusawa M
AD  - Department of Radiology, Kumamoto City Hospital 1-1-60, Koto, Higashi-ku, 
      Kumamoto City, 862-0909, Japan.
FAU - Tanoue, S
AU  - Tanoue S
AD  - Department of Radiology, Kumamoto City Hospital 1-1-60, Koto, Higashi-ku, 
      Kumamoto City, 862-0909, Japan; Department of Diagnostic Radiology, Graduate 
      School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 
      860-8556, Japan.
FAU - Utsunomiya, D
AU  - Utsunomiya D
AD  - Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto 
      University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
FAU - Yamashita, Y
AU  - Yamashita Y
AD  - Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto 
      University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
LA  - eng
PT  - Journal Article
DEP - 20171010
PL  - England
TA  - Clin Radiol
JT  - Clinical radiology
JID - 1306016
RN  - 0 (Contrast Media)
RN  - 17E17JBP8L (iomeprol)
RN  - 4419T9MX03 (Iohexol)
RN  - JR13W81H44 (Iopamidol)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Algorithms
MH  - *Contrast Media
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Iohexol
MH  - Iopamidol/analogs & derivatives
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/*diagnostic imaging
MH  - *Radiation Dosage
MH  - Radiographic Image Enhancement/methods
MH  - Retrospective Studies
MH  - Tomography, X-Ray Computed/*methods
MH  - Whole Body Imaging/*methods
EDAT- 2017/10/17 06:00
MHDA- 2018/10/16 06:00
CRDT- 2017/10/15 06:00
PHST- 2017/02/02 00:00 [received]
PHST- 2017/07/04 00:00 [revised]
PHST- 2017/09/12 00:00 [accepted]
PHST- 2017/10/17 06:00 [pubmed]
PHST- 2018/10/16 06:00 [medline]
PHST- 2017/10/15 06:00 [entrez]
AID - S0009-9260(17)30465-8 [pii]
AID - 10.1016/j.crad.2017.09.006 [doi]
PST - ppublish
SO  - Clin Radiol. 2018 Feb;73(2):217.e7-217.e16. doi: 10.1016/j.crad.2017.09.006. Epub 
      2017 Oct 10.