PMID- 29030069
OWN - NLM
STAT- MEDLINE
DCOM- 20190726
LR  - 20190726
IS  - 1090-2147 (Electronic)
IS  - 0278-2626 (Linking)
VI  - 131
DP  - 2019 Apr
TI  - Sex differences and menstrual cycle effects in cognitive and sensory resting 
      state networks.
PG  - 66-73
LID - S0278-2626(17)30183-5 [pii]
LID - 10.1016/j.bandc.2017.09.003 [doi]
AB  - It has not yet been established if resting state (RS) connectivity reflects 
      stable characteristics of the brain, or if it is modulated by the psychological 
      and/or physiological state of the participant. Based on research demonstrating 
      sex hormonal effects in task-related brain activity, the present study aimed to 
      investigate corresponding differences in RS networks. RS functional Magnetic 
      Resonance Imaging (RS fMRI) was conducted in women during three different 
      menstrual cycle phases, while men underwent three repeated RS fMRI testing 
      sessions. Independent component analysis was used to identify the default mode 
      network (DMN) and an auditory RS network. For the DMN, RS connectivity was stable 
      across testing sessions in men, but varied across the menstrual cycle in women. 
      For the auditory network (AN), retest reliable sex difference was found. Although 
      RS activity in the DMN has been interpreted as trait characteristic of functional 
      brain organization, these findings suggest that RS activity in networks involving 
      frontal areas might be less stable than in sensory-based networks and can 
      dynamically fluctuate. This also implies that some of the previously reported 
      effects of sex hormones on task-related activity might to some extent be mediated 
      by cycle-related fluctuations in RS activity, especially when frontal areas are 
      involved.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Weis, Susanne
AU  - Weis S
AD  - Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University 
      Dusseldorf, Dusseldorf, Germany; Institute of Neuroscience and Medicine, Brain & 
      Behaviour (INM-7), Research Centre Julich, Julich, Germany; Department of 
      Psychology, Durham University, UK; Durham University Neuroimaging Centre (DUNIC), 
      UK. Electronic address: S.Weis@fz-juelich.de.
FAU - Hodgetts, Sophie
AU  - Hodgetts S
AD  - Department of Psychology, Durham University, UK; Durham University Neuroimaging 
      Centre (DUNIC), UK.
FAU - Hausmann, Markus
AU  - Hausmann M
AD  - Department of Psychology, Durham University, UK; Durham University Neuroimaging 
      Centre (DUNIC), UK.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171010
PL  - United States
TA  - Brain Cogn
JT  - Brain and cognition
JID - 8218014
RN  - 4G7DS2Q64Y (Progesterone)
RN  - 4TI98Z838E (Estradiol)
MH  - Adolescent
MH  - Adult
MH  - Attention/physiology
MH  - Brain/*diagnostic imaging/physiology
MH  - Brain Mapping/methods
MH  - Cognition/*physiology
MH  - Estradiol/blood
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Menstrual Cycle/*physiology
MH  - Progesterone/blood
MH  - *Sex Characteristics
MH  - Young Adult
OTO - NOTNLM
OT  - Default mode network
OT  - Resting state
OT  - Sex differences
OT  - Sex hormones
OT  - fMRI
EDAT- 2017/10/17 06:00
MHDA- 2019/07/28 06:00
CRDT- 2017/10/15 06:00
PHST- 2017/04/28 00:00 [received]
PHST- 2017/08/24 00:00 [revised]
PHST- 2017/09/05 00:00 [accepted]
PHST- 2017/10/17 06:00 [pubmed]
PHST- 2019/07/28 06:00 [medline]
PHST- 2017/10/15 06:00 [entrez]
AID - S0278-2626(17)30183-5 [pii]
AID - 10.1016/j.bandc.2017.09.003 [doi]
PST - ppublish
SO  - Brain Cogn. 2019 Apr;131:66-73. doi: 10.1016/j.bandc.2017.09.003. Epub 2017 Oct 
      10.