PMID- 29033412
OWN - NLM
STAT- MEDLINE
DCOM- 20180611
LR  - 20181113
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 56
IP  - 24
DP  - 2017 Dec 15
TI  - Emergency Caesarean Section Saved Both an Anti-MuSK Antibody-positive Myasthenia 
      Gravis Mother with Pregnancy-induced Hypertension and Her Premature Baby.
PG  - 3361-3364
LID - 10.2169/internalmedicine.8636-16 [doi]
AB  - We herein report the case of a 46-year-old pregnant woman with anti-muscle 
      specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed 
      pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 
      5 days of pregnancy, and who underwent an emergency caesarean section (CS). Her 
      MG symptoms gradually improved in the subsequent weeks. The premature baby with 
      positive MuSK antibodies was successfully delivered, but the male baby required 
      temporary artificial ventilation. However, his condition also gradually improved 
      over time. The present case suggests that an emergency CS could rescue both the 
      mother, who was in critical condition, and the prematurely born baby, even when 
      suffering from acute respiratory insufficiency.
FAU - Takahashi, Yoshiaki
AU  - Takahashi Y
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Yamashita, Toru
AU  - Yamashita T
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Morihara, Ryuta
AU  - Morihara R
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Nakano, Yumiko
AU  - Nakano Y
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Sato, Kota
AU  - Sato K
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Takemoto, Mami
AU  - Takemoto M
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Hishikawa, Nozomi
AU  - Hishikawa N
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Ohta, Yasuyuki
AU  - Ohta Y
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Hayata, Kei
AU  - Hayata K
AD  - Department of Obstetrics and Gynecology, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Science, Japan.
FAU - Masuyama, Hisashi
AU  - Masuyama H
AD  - Department of Obstetrics and Gynecology, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Science, Japan.
FAU - Okamura, Tomoka
AU  - Okamura T
AD  - Department of Prediatrics, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Washio, Yosuke
AU  - Washio Y
AD  - Department of Prediatrics, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
FAU - Abe, Koji
AU  - Abe K
AD  - Department of Neurology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Science, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20171016
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Autoantibodies)
RN  - 0 (Receptors, Cholinergic)
RN  - EC 2.7.10.1 (MUSK protein, human)
RN  - EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases)
SB  - IM
MH  - Autoantibodies/immunology
MH  - Cesarean Section/*methods
MH  - Female
MH  - Humans
MH  - Hypertension, Pregnancy-Induced/*surgery
MH  - Infant, Newborn
MH  - Male
MH  - Middle Aged
MH  - Mothers
MH  - Myasthenia Gravis/*complications/*surgery
MH  - Pregnancy
MH  - Receptor Protein-Tyrosine Kinases/*immunology
MH  - Receptors, Cholinergic/*immunology
PMC - PMC5790728
OTO - NOTNLM
OT  - anti-MuSK antibody
OT  - emergency caesarean section
OT  - myasthenia gravis
OT  - pregnancy-induced hypertension
OT  - premature baby
EDAT- 2017/10/17 06:00
MHDA- 2018/06/12 06:00
PMCR- 2017/12/15
CRDT- 2017/10/17 06:00
PHST- 2017/10/17 06:00 [pubmed]
PHST- 2018/06/12 06:00 [medline]
PHST- 2017/10/17 06:00 [entrez]
PHST- 2017/12/15 00:00 [pmc-release]
AID - 10.2169/internalmedicine.8636-16 [doi]
PST - ppublish
SO  - Intern Med. 2017 Dec 15;56(24):3361-3364. doi: 10.2169/internalmedicine.8636-16. 
      Epub 2017 Oct 16.