PMID- 29033508
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220409
IS  - 1011-6842 (Print)
IS  - 1011-6842 (Linking)
VI  - 33
IP  - 4
DP  - 2017 Jul
TI  - Predictors of Mortality in Elderly Patients with Non-ST Elevation Acute Coronary 
      Syndrome - Data from Taiwan Acute Coronary Syndrome Full Spectrum Registry.
PG  - 377-383
AB  - BACKGROUND: Some difficulties and variations remain associated with the care of 
      elderly patients with non-ST elevation acute coronary syndrome (NSTE-ACS). 
      METHODS: We included 1470 patients from a Taiwan nationwide registry who 
      fulfilled the criteria of NSTE-ACS, and stratified these patients by age and 
      evaluated the treatment, complications and outcomes in different age groups. 
      Furthermore, we analyzed risk factors and standards of care to determine the 
      predictors of mortality. RESULTS: Patients >/= 75 years of age (n = 396) had 
      significantly higher incidences of 90-day mortality [odd ratio (OR) = 4.5 
      (1.2-16.3), p = 0.023] and 1-year mortality [OR = 4.9 (2.0-12.3), p = 0.001] 
      compared with those patients 45-64 years of age (n = 595). In the patients >/= 75 
      years of age, previous myocardial infarction (MI) [OR = 3.3 (1.1-9.8), p = 
      0.035], statins [OR = 0.35 (0.1-0.9), p = 0.037], left ventricular ejection 
      fraction (LVEF) < 35% [OR = 3.9 (1.5-10.4), p = 0.006] were associated with 
      90-day mortality. Furthermore, previous MI [OR = 4.0 (1.3-12.6), p = 0.019] was 
      an independent predictor of 90-day mortality. Age [OR = 1.1 (1.03-1.2), p = 
      0.002], previous MI [OR = 2.2 (1.1-4.4), p = 0.034], angiotensin-converting 
      enzyme inhibitor or angiotensin receptor blocker [OR = 0.5 (0.3-0.9), p = 0.028], 
      and LVEF < 35% [OR = 4.3 (1.9-9.5), p < 0.001] were associated with 1-year 
      mortality. Furthermore, previous MI [OR = 2.6 (1.1-6.5), p = 0.037], LVEF < 35% 
      [OR = 4.7 (1.5-14.4), p = 0.007] and percutaneous coronary intervention(PCI) or 
      not [OR = 0.3 (0.1-0.9), p = 0.021] were independent predictors of 1-year 
      mortality. CONCLUSIONS: Previous MI, LVEF < 35% and PCI or not could predict 
      1-year mortality in advanced elderly patients with NSTE-ACS. Despite their 
      elevated morbidities and complications, PCI was still beneficial for these 
      patients.
FAU - Wei, Cheng-Chun
AU  - Wei CC
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho Su 
      Memorial Hospital, Taipei.
FAU - Lee, Shih-Huang
AU  - Lee SH
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho Su 
      Memorial Hospital, Taipei.
AD  - School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
LA  - eng
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Acta Cardiol Sin
JT  - Acta Cardiologica Sinica
JID - 101687085
PMC - PMC5534417
OTO - NOTNLM
OT  - Acute coronary syndrome
OT  - Age
OT  - Outcome
OT  - Predictor
EDAT- 2017/10/17 06:00
MHDA- 2017/10/17 06:01
PMCR- 2017/07/01
CRDT- 2017/10/17 06:00
PHST- 2017/10/17 06:00 [entrez]
PHST- 2017/10/17 06:00 [pubmed]
PHST- 2017/10/17 06:01 [medline]
PHST- 2017/07/01 00:00 [pmc-release]
AID - 10.6515/acs20170126a [doi]
PST - ppublish
SO  - Acta Cardiol Sin. 2017 Jul;33(4):377-383. doi: 10.6515/acs20170126a.