PMID- 29040883
OWN - NLM
STAT- MEDLINE
DCOM- 20190318
LR  - 20220408
IS  - 1557-8615 (Electronic)
IS  - 0883-9441 (Linking)
VI  - 44
DP  - 2018 Apr
TI  - Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for emergency cardiac 
      support.
PG  - 31-38
LID - S0883-9441(17)30997-8 [pii]
LID - 10.1016/j.jcrc.2017.10.011 [doi]
AB  - PURPOSE: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may provide 
      benefit to patients in refractory cardiac arrest and cardiogenic shock. We aim to 
      summarize our center's 6-year experience with resuscitative VA-ECMO. MATERIALS 
      AND METHODS: A retrospective medical record review (April 2009 to 2015) was 
      performed on consecutive non-cardiotomy patients who were managed with VA-ECMO 
      due to refractory in- or out-of-hospital cardiac (IHCA/OHCA) arrest (E-CPR) or 
      refractory cardiogenic shock (E-CS) with or without preceding cardiac arrest. Our 
      primary outcome was survival to hospital discharge and good neurological status 
      (Cerebral Performance Category 1-2). RESULTS: There were a total of 22 patients 
      who met inclusion criteria of whom 9 received E-CPR (8 IHCA, 1 OHCA) and 13 
      received E-CS. The median age for E-CPR patients was 52 [IQR 45, 58] years, and 
      54 [IQR 38, 64] years for E-CS patients. Cardiac arrest duration was 70.33 (SD 
      39.56) min for the E-CPR patients, and 24.67 (SD 26.73) min for the 9 patients 
      treated with E-CS who had previously arrested. Initial cardiac arrest rhythms 
      were pulseless electrical activity (39%), ventricular fibrillation (33%), or 
      ventricular tachycardia (28%). A total of 18/22 patients were successfully weaned 
      from VA-ECMO (78%); 16 patients survived to hospital discharge (73%) with 15 in 
      good neurological condition. CONCLUSION: The initiation of VA-ECMO at our center 
      for treatment of refractory cardiac arrest and cardiogenic shock yielded a high 
      proportion of survivors and favorable neurological outcomes.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Sun, Terri
AU  - Sun T
AD  - Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, 
      University of British Columbia, Vancouver General Hospital, Rm 330, 910 W 10th 
      Ave, V5Z 1M9 Vancouver, British Columbia, Canada. Electronic address: 
      terri.sun@alumni.ubc.ca.
FAU - Guy, Andrew
AU  - Guy A
AD  - Faculty of Medicine, University of British Columbia, 317-2194 Health Sciences 
      Mall, V6T 1Z3 Vancouver, British Columbia, Canada.
FAU - Sidhu, Amandeep
AU  - Sidhu A
AD  - Perfusion Services, Vancouver General Hospital, 910 W 10th Ave, V5Z 1M9 
      Vancouver, British Columbia, Canada.
FAU - Finlayson, Gordon
AU  - Finlayson G
AD  - Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, 
      University of British Columbia, Vancouver General Hospital, Rm 330, 910 W 10th 
      Ave, V5Z 1M9 Vancouver, British Columbia, Canada; Department of Medicine, 
      Division of Critical Care, Faculty of Medicine, University of British Columbia, 
      Critical Care, Vancouver General Hospital, 2438-855 West 12th Avenue, V5Z 1M9 
      Vancouver, British Columbia, Canada.
FAU - Grunau, Brian
AU  - Grunau B
AD  - Department of Emergency Medicine, University of British Columbia, Rm 3300, 910 W 
      10th Ave, V5Z 1M9 Vancouver, British Columbia, Canada.
FAU - Ding, Lillian
AU  - Ding L
AD  - Cardiac Services BC, Provincial Health Services Authority, 700-1380 Burrard 
      Street, V6Z 2H3 Vancouver, British Columbia, Canada.
FAU - Harle, Saida
AU  - Harle S
AD  - Cardiac Services BC, Provincial Health Services Authority, 700-1380 Burrard 
      Street, V6Z 2H3 Vancouver, British Columbia, Canada.
FAU - Dewar, Leith
AU  - Dewar L
AD  - Cardiovascular Surgery, Faculty of Medicine, University of British Columbia, 
      Cardiac Surgery, Vancouver General Hospital, 950 West 10th Avenue, V5Z 1M9 
      Vancouver, British Columbia, Canada.
FAU - Cook, Richard
AU  - Cook R
AD  - Cardiovascular Surgery, Faculty of Medicine, University of British Columbia, 
      Cardiac Surgery, Vancouver General Hospital, 950 West 10th Avenue, V5Z 1M9 
      Vancouver, British Columbia, Canada.
FAU - Kanji, Hussein D
AU  - Kanji HD
AD  - Faculty of Medicine, University of British Columbia, 317-2194 Health Sciences 
      Mall, V6T 1Z3 Vancouver, British Columbia, Canada; Department of Medicine, 
      Division of Critical Care, Faculty of Medicine, University of British Columbia, 
      Critical Care, Vancouver General Hospital, 2438-855 West 12th Avenue, V5Z 1M9 
      Vancouver, British Columbia, Canada.
LA  - eng
PT  - Journal Article
DEP - 20171012
PL  - United States
TA  - J Crit Care
JT  - Journal of critical care
JID - 8610642
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiopulmonary Resuscitation/*methods
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Female
MH  - Heart Arrest/*therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nervous System Diseases/diagnosis
MH  - Outcome Assessment, Health Care
MH  - Retrospective Studies
MH  - Shock, Cardiogenic/*therapy
MH  - Survival Analysis
OTO - NOTNLM
OT  - Cardiac arrest
OT  - Cardiogenic shock
OT  - E-CPR
OT  - E-CS
OT  - ECLS
OT  - Extracorporeal cardiopulmonary resuscitation
OT  - Extracorporeal life support
OT  - VA-ECMO
OT  - Veno-arterial extracorporeal membrane oxygenation
EDAT- 2017/10/19 06:00
MHDA- 2019/03/19 06:00
CRDT- 2017/10/18 06:00
PHST- 2017/07/06 00:00 [received]
PHST- 2017/09/30 00:00 [revised]
PHST- 2017/10/09 00:00 [accepted]
PHST- 2017/10/19 06:00 [pubmed]
PHST- 2019/03/19 06:00 [medline]
PHST- 2017/10/18 06:00 [entrez]
AID - S0883-9441(17)30997-8 [pii]
AID - 10.1016/j.jcrc.2017.10.011 [doi]
PST - ppublish
SO  - J Crit Care. 2018 Apr;44:31-38. doi: 10.1016/j.jcrc.2017.10.011. Epub 2017 Oct 
      12.