PMID- 29048786
OWN - NLM
STAT- MEDLINE
DCOM- 20181114
LR  - 20181114
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 35
IP  - 6
DP  - 2017 Jun 8
TI  - [Simultaneous determination of five mycotoxins in various grains and their 
      products by liquid chromatography-tandem mass spectrometry with isotope internal 
      standard].
PG  - 601-607
LID - 10.3724/SP.J.1123.2016.12028 [doi]
AB  - A rapid method was established for the determination of zearalenone (ZON), 
      nivalenol (NIV), deoxynivalenol (DON), 3-acetyl-deoxynivalenol (3-ACDON) and 
      15-acetyl-deoxynivalenol (15-ACDON) in various grains and their products by 
      liquid chromatography-tandem mass spectrometry (LC-MS/MS). The samples were 
      extracted by acetonitrile-water (84:16, v/v), and cleaned-up by multifunctional 
      column without any further step. The separation was carried out on an Acquity 
      UPLC((R)) BEH C18 column (100 mmx2.1 mm, 1.7 mum) with gradient elution using 
      acetonitrile-water as mobile phases. The analytes were quantified by isotope 
      internal standard method. The correlation coefficients (r(2)) were all above 
      0.99. The limits of detection (LODs, S/N=3) ranged from 5 mug/kg to 20 mug/kg. The 
      recoveries of the five mycotoxins spiked in blank grain and its product samples 
      varied from 84.2% to 114.5%, with the relative standard deviations (RSDs) of 
      0.4%-9.9% (n=6). The method is accurate, efficient, sensitive and practical.
FAU - Gao, Bei
AU  - Gao B
AD  - Chinese Oil & Foodstuffs Corporation (COFCO) Nutrition and Health Research 
      Institute, Beijing Key Laboratory of Nutrition Health and Food Safety, Beijing 
      102209, China.
FAU - Jiang, Deming
AU  - Jiang D
AD  - Chinese Oil & Foodstuffs Corporation (COFCO) Nutrition and Health Research 
      Institute, Beijing Key Laboratory of Nutrition Health and Food Safety, Beijing 
      102209, China.
FAU - Yang, Yongtan
AU  - Yang Y
AD  - Chinese Oil & Foodstuffs Corporation (COFCO) Nutrition and Health Research 
      Institute, Beijing Key Laboratory of Nutrition Health and Food Safety, Beijing 
      102209, China. yangyongtan@cofco.com.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Isotopes)
RN  - 0 (Mycotoxins)
RN  - 0 (Trichothecenes)
RN  - 50722-38-8 (3-acetyldeoxynivalenol)
RN  - 5W827M159J (Zearalenone)
RN  - 5WOP02RM1U (nivalenol)
RN  - 88337-96-6 (15-acetyldeoxynivalenol)
RN  - JT37HYP23V (deoxynivalenol)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Chromatography, Liquid
MH  - Edible Grain/*microbiology
MH  - Isotopes
MH  - Limit of Detection
MH  - Mycotoxins/*analysis
MH  - *Tandem Mass Spectrometry
MH  - Trichothecenes/analysis
MH  - Zearalenone
OTO - NOTNLM
OT  - grains and their products
OT  - isotope internal standard
OT  - liquid chromatography-tandem mass spectrometry (LC-MS/MS)
OT  - mycotoxins
EDAT- 2017/10/20 06:00
MHDA- 2018/11/15 06:00
CRDT- 2017/10/20 06:00
PHST- 2017/10/20 06:00 [entrez]
PHST- 2017/10/20 06:00 [pubmed]
PHST- 2018/11/15 06:00 [medline]
AID - 10.3724/SP.J.1123.2016.12028 [doi]
PST - ppublish
SO  - Se Pu. 2017 Jun 8;35(6):601-607. doi: 10.3724/SP.J.1123.2016.12028.