PMID- 29059101
OWN - NLM
STAT- MEDLINE
DCOM- 20190808
LR  - 20220409
IS  - 1539-2864 (Electronic)
IS  - 0275-004X (Linking)
VI  - 38
IP  - 12
DP  - 2018 Dec
TI  - PREVALENCE OF POLYPOIDAL CHOROIDAL VASCULOPATHY IN WHITE PATIENTS WITH EXUDATIVE 
      AGE-RELATED MACULAR DEGENERATION: Systematic Review and Meta-Analysis.
PG  - 2363-2371
LID - 10.1097/IAE.0000000000001872 [doi]
AB  - PURPOSE: Polypoidal choroidal vasculopathy (PCV) is a disease with significant 
      inter-ethnical differences. In this study, we systematically review the 
      literature on the prevalence of PCV in whites referred with a diagnosis of 
      exudative age-related macular degeneration (AMD). METHODS: We searched PubMed, 
      Embase, the Cochrane Library, and the Web of Science on 24 March, 2017 for 
      studies evaluating the prevalence of PCV in white patients with exudative AMD. 
      Data extraction and risk of bias assessments were performed in duplicate. Studies 
      were included for a qualitative review and a meta-analysis, including subgroup 
      analysis for differences in age and sex. RESULTS: We included data from 11 
      studies (>2,200 participants). For diagnosis, indocyanine green angiography was 
      used together with a set of supporting criteria on fundus examination and optical 
      coherence tomography. Extramacular location was more prevalent in eyes with PCV. 
      Drusen was present in the fellow eye in 17% to 27%. Pooled prevalence of PCV in 
      white patients with exudative AMD was 8.7% (confidence interval 95%: 7.2%-10.3%). 
      Patients with PCV were 3.7 years (confidence interval 95%: 2.1 years-5.3 years) 
      younger than those with other exudative AMD. Sex did not differ significantly. 
      CONCLUSION: Polypoidal choroidal vasculopathy is not a rare subtype of exudative 
      AMD in whites-it is present in approximately one in 11 patients.
FAU - Lorentzen, Thomas D
AU  - Lorentzen TD
AD  - Clinical Eye Research Division, Department of Ophthalmology, Zealand University 
      Hospital, Roskilde, Denmark.
AD  - Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 
      Denmark.
FAU - Subhi, Yousif
AU  - Subhi Y
AD  - Clinical Eye Research Division, Department of Ophthalmology, Zealand University 
      Hospital, Roskilde, Denmark.
AD  - Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 
      Denmark.
FAU - Sorensen, Torben L
AU  - Sorensen TL
AD  - Clinical Eye Research Division, Department of Ophthalmology, Zealand University 
      Hospital, Roskilde, Denmark.
AD  - Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 
      Denmark.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - United States
TA  - Retina
JT  - Retina (Philadelphia, Pa.)
JID - 8309919
MH  - Choroid/*blood supply
MH  - Choroid Diseases/complications/diagnosis/*epidemiology
MH  - Fluorescein Angiography/methods
MH  - Fundus Oculi
MH  - Global Health
MH  - Humans
MH  - Macula Lutea/pathology
MH  - Polyps/complications/diagnosis/*epidemiology
MH  - Prevalence
MH  - Tomography, Optical Coherence
MH  - Wet Macular Degeneration/*complications/diagnosis
EDAT- 2017/10/24 06:00
MHDA- 2019/08/09 06:00
CRDT- 2017/10/24 06:00
PHST- 2017/10/24 06:00 [pubmed]
PHST- 2019/08/09 06:00 [medline]
PHST- 2017/10/24 06:00 [entrez]
AID - 10.1097/IAE.0000000000001872 [doi]
PST - ppublish
SO  - Retina. 2018 Dec;38(12):2363-2371. doi: 10.1097/IAE.0000000000001872.