PMID- 29061204
OWN - NLM
STAT- MEDLINE
DCOM- 20171121
LR  - 20230916
IS  - 1469-4409 (Electronic)
IS  - 0950-2688 (Print)
IS  - 0950-2688 (Linking)
VI  - 145
IP  - 15
DP  - 2017 Nov
TI  - A spatial and temporal analysis of paediatric central nervous system infections 
      from 2005 to 2015 in Ho Chi Minh City, Vietnam.
PG  - 3307-3317
LID - 10.1017/S095026881700228X [doi]
AB  - Central nervous system infections (CNSI) are a leading cause of death and 
      long-term disability in children. Using ICD-10 data from 2005 to 2015 from three 
      central hospitals in Ho Chi Minh City (HCMC), Vietnam, we exploited generalized 
      additive mixed models (GAMM) to examine the spatial-temporal distribution and 
      spatial and climatic risk factors of paediatric CNSI, excluding tuberculous 
      meningitis, in this setting. From 2005 to 2015, there were 9469 cases of 
      paediatric CNSI; 33% were ⩽1 year old at admission and were mainly diagnosed with 
      presumed bacterial CNSI (BI) (79%), the remainder were >1 year old and mainly 
      diagnosed with presumed non-bacterial CNSI (non-BI) (59%). The urban districts of 
      HCMC in proximity to the hospitals as well as some outer districts had the 
      highest incidences of BI and non-BI; BI incidence was higher in the dry season. 
      Monthly BI incidence exhibited a significant decreasing trend over the study. 
      Both BI and non-BI were significantly associated with lags in monthly average 
      temperature, rainfall, and river water level. Our findings add new insights into 
      this important group of infections in Vietnam, and highlight where resources for 
      the prevention and control of paediatric CNSI should be allocated.
FAU - Ho, N T
AU  - Ho NT
AD  - Columbia University Medical Center,New York City,New York,USA.
FAU - Hoang, V M T
AU  - Hoang VMT
AD  - Children's Hospital 2,Ho Chi Minh City,Vietnam.
FAU - Le, N N T
AU  - Le NNT
AD  - Children's Hospital 1,Ho Chi Minh City,Vietnam.
FAU - Nguyen, D T
AU  - Nguyen DT
AD  - Hospital for Tropical Diseases,Ho Chi Minh City,Vietnam.
FAU - Tran, A
AU  - Tran A
AD  - Saint Louis University,Saint Louis,Missouri,USA.
FAU - Kaki, D
AU  - Kaki D
AD  - Princeton University,Princeton,New Jersey,USA.
FAU - Tran, P M
AU  - Tran PM
AD  - Oxford University Clinical Research Unit,Wellcome Trust Major Overseas 
      Programme,Ho Chi Minh City,Vietnam.
FAU - Thompson, C N
AU  - Thompson CN
AD  - Oxford University Clinical Research Unit,Wellcome Trust Major Overseas 
      Programme,Ho Chi Minh City,Vietnam.
FAU - Ngo, M N Q
AU  - Ngo MNQ
AD  - Children's Hospital 1,Ho Chi Minh City,Vietnam.
FAU - Truong, K H
AU  - Truong KH
AD  - Children's Hospital 1,Ho Chi Minh City,Vietnam.
FAU - Nguyen, H T
AU  - Nguyen HT
AD  - Children's Hospital 1,Ho Chi Minh City,Vietnam.
FAU - Ha, T M
AU  - Ha TM
AD  - Children's Hospital 2,Ho Chi Minh City,Vietnam.
FAU - Nguyen, C V V
AU  - Nguyen CVV
AD  - Hospital for Tropical Diseases,Ho Chi Minh City,Vietnam.
FAU - Thwaites, G E
AU  - Thwaites GE
AD  - Oxford University Clinical Research Unit,Wellcome Trust Major Overseas 
      Programme,Ho Chi Minh City,Vietnam.
FAU - Thakur, K T
AU  - Thakur KT
AD  - Columbia University Medical Center,New York City,New York,USA.
FAU - Hesdorffer, D
AU  - Hesdorffer D
AD  - Columbia University Medical Center,New York City,New York,USA.
FAU - Baker, S
AU  - Baker S
AD  - Oxford University Clinical Research Unit,Wellcome Trust Major Overseas 
      Programme,Ho Chi Minh City,Vietnam.
LA  - eng
GR  - WT_/Wellcome Trust/United Kingdom
GR  - 100087/Z/12/Z/WT_/Wellcome Trust/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171024
PL  - England
TA  - Epidemiol Infect
JT  - Epidemiology and infection
JID - 8703737
SB  - IM
MH  - Adolescent
MH  - Central Nervous System Infections/*epidemiology/microbiology
MH  - Child
MH  - Child, Preschool
MH  - Encephalitis, Viral/epidemiology
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Infant
MH  - Male
MH  - Meningitis, Bacterial/epidemiology
MH  - Meningitis, Viral/epidemiology
MH  - Risk Factors
MH  - Seasons
MH  - Spatio-Temporal Analysis
MH  - Urban Population/statistics & numerical data
MH  - Vietnam/epidemiology
PMC - PMC9148745
OTO - NOTNLM
OT  - Encephalitis
OT  - epidemiology
OT  - meningitis
OT  - paediatric
OT  - spatial temporal
EDAT- 2017/10/25 06:00
MHDA- 2017/11/29 06:00
PMCR- 2022/05/29
CRDT- 2017/10/25 06:00
PHST- 2017/10/25 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
PHST- 2017/10/25 06:00 [entrez]
PHST- 2022/05/29 00:00 [pmc-release]
AID - S095026881700228X [pii]
AID - 00228 [pii]
AID - 10.1017/S095026881700228X [doi]
PST - ppublish
SO  - Epidemiol Infect. 2017 Nov;145(15):3307-3317. doi: 10.1017/S095026881700228X. 
      Epub 2017 Oct 24.