PMID- 29068869
OWN - NLM
STAT- MEDLINE
DCOM- 20171103
LR  - 20190113
IS  - 1536-3678 (Electronic)
IS  - 1077-4114 (Linking)
VI  - 39
IP  - 8
DP  - 2017 Nov
TI  - Dural Venous Sinus Thrombosis and Pulmonary Embolism Following Immunoglobulin 
      Treatment in Pediatric Patient With Immune Thrombocytopenic Purpura.
PG  - e508-e511
LID - 10.1097/MPH.0000000000000841 [doi]
AB  - Intravenous immunoglobulin (IVIG) is a widely used agent as the first choice of 
      treatment of immune thrombocytopenic purpura (ITP). IVIG has several side 
      effects, but it is a relatively safe treatment. Life-threatening thrombosis has 
      been reported in adults and rarely in children. We report a case of a 14-year-old 
      boy with dural venous sinus thrombosis and pulmonary embolism after treatment 
      with IVIG for ITP. The patient was treated with low-molecular-weight heparin 
      followed by warfarin and the symptoms were recovered. If a patient with ITP shows 
      mental change or respiratory difficulty, we should consider thrombosis as well as 
      hemorrhage.
FAU - Park, Kyung Mi
AU  - Park KM
AD  - Department of Pediatrics, Pusan National University Children's Hospital, Yangsan, 
      Korea.
FAU - Yang, Eu Jeen
AU  - Yang EJ
FAU - Lim, Young Tak
AU  - Lim YT
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Pediatr Hematol Oncol
JT  - Journal of pediatric hematology/oncology
JID - 9505928
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 5Q7ZVV76EI (Warfarin)
SB  - IM
MH  - Adolescent
MH  - Anticoagulants/therapeutic use
MH  - Biopsy
MH  - Bone Marrow/pathology
MH  - Hematologic Tests
MH  - Heparin, Low-Molecular-Weight/therapeutic use
MH  - Humans
MH  - Immunoglobulins, Intravenous/administration & dosage
MH  - Magnetic Resonance Angiography
MH  - Male
MH  - Pulmonary Embolism/*diagnosis/drug therapy/*etiology
MH  - Purpura, Thrombocytopenic, Idiopathic/*complications/diagnosis/therapy
MH  - Sinus Thrombosis, Intracranial/*diagnosis/drug therapy/*etiology
MH  - Tomography, X-Ray Computed
MH  - Treatment Outcome
MH  - Venous Thrombosis/diagnosis/etiology
MH  - Warfarin/therapeutic use
EDAT- 2017/10/27 06:00
MHDA- 2017/11/04 06:00
CRDT- 2017/10/26 06:00
PHST- 2017/10/26 06:00 [entrez]
PHST- 2017/10/27 06:00 [pubmed]
PHST- 2017/11/04 06:00 [medline]
AID - 00043426-201711000-00039 [pii]
AID - 10.1097/MPH.0000000000000841 [doi]
PST - ppublish
SO  - J Pediatr Hematol Oncol. 2017 Nov;39(8):e508-e511. doi: 
      10.1097/MPH.0000000000000841.