PMID- 29070509
OWN - NLM
STAT- MEDLINE
DCOM- 20180727
LR  - 20190806
IS  - 1532-298X (Electronic)
IS  - 1040-4651 (Print)
IS  - 1040-4651 (Linking)
VI  - 29
IP  - 11
DP  - 2017 Nov
TI  - Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce 
      Stomatal Development in Arabidopsis.
PG  - 2817-2830
LID - 10.1105/tpc.17.00371 [doi]
AB  - Stomata are epidermal openings that facilitate plant-atmosphere gas exchange 
      during photosynthesis, respiration, and water evaporation. Stomatal 
      differentiation and patterning are spatially and temporally regulated by the 
      master regulators SPEECHLESS (SPCH), MUTE, and FAMA, which constitute a central 
      gene regulatory network along with Inducer of CBF Expression (ICE) transcription 
      factors for this developmental process. Stomatal development is also profoundly 
      influenced by environmental conditions, such as light, temperature, and humidity. 
      Light induces stomatal development, and various photoreceptors modulate this 
      response. However, it is unknown how light is functionally linked with the master 
      regulatory network. Here, we demonstrate that, under dark conditions, the E3 
      ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1) degrades ICE proteins 
      through ubiquitination pathways in leaf abaxial epidermal cells in Arabidopsis 
      thaliana Accordingly, the ICE proteins accumulate in the nuclei of leaf abaxial 
      epidermal cells in COP1-defective mutants, which constitutively produce stomata. 
      Notably, light in the blue, red, and far-red wavelength ranges suppresses the 
      COP1-mediated degradation of the ICE proteins to induce stomatal development. 
      These observations indicate that light is directly linked with the ICE-directed 
      signaling module, via the COP1-mediated protein surveillance system, in the 
      modulation of stomatal development.
CI  - (c) 2017 American Society of Plant Biologists. All rights reserved.
FAU - Lee, Jae-Hyung
AU  - Lee JH
AUID- ORCID: 0000-0002-0207-8181
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea.
FAU - Jung, Jae-Hoon
AU  - Jung JH
AUID- ORCID: 0000-0002-8558-8397
AD  - Sainsbury Laboratory, University of Cambridge, Cambridge CB2 1LR, United Kingdom.
FAU - Park, Chung-Mo
AU  - Park CM
AUID- ORCID: 0000-0001-8841-8361
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea 
      cmpark@snu.ac.kr.
AD  - Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, 
      Korea.
LA  - eng
PT  - Journal Article
DEP - 20171025
PL  - England
TA  - Plant Cell
JT  - The Plant cell
JID - 9208688
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (ICE1 protein, Arabidopsis)
RN  - 0 (Transcription Factors)
RN  - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis)
RN  - EC 2.3.2.27 (Ubiquitin-Protein Ligases)
SB  - IM
CIN - Plant Cell. 2017 Nov;29(11):2680-2681. PMID: 29133463
MH  - Arabidopsis/genetics/growth & development/*metabolism
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - Gene Expression Regulation, Developmental/radiation effects
MH  - Gene Expression Regulation, Plant/radiation effects
MH  - *Light
MH  - Plant Stomata/genetics/growth & development/*metabolism
MH  - Plants, Genetically Modified
MH  - Proteolysis/radiation effects
MH  - Signal Transduction/genetics/radiation effects
MH  - Transcription Factors/genetics/*metabolism
MH  - Ubiquitin-Protein Ligases/genetics/*metabolism
PMC - PMC5728130
EDAT- 2017/10/27 06:00
MHDA- 2018/07/28 06:00
PMCR- 2018/11/01
CRDT- 2017/10/27 06:00
PHST- 2017/05/10 00:00 [received]
PHST- 2017/10/06 00:00 [revised]
PHST- 2017/10/24 00:00 [accepted]
PHST- 2017/10/27 06:00 [pubmed]
PHST- 2018/07/28 06:00 [medline]
PHST- 2017/10/27 06:00 [entrez]
PHST- 2018/11/01 00:00 [pmc-release]
AID - tpc.17.00371 [pii]
AID - TPC2017RA00371DR2 [pii]
AID - 10.1105/tpc.17.00371 [doi]
PST - ppublish
SO  - Plant Cell. 2017 Nov;29(11):2817-2830. doi: 10.1105/tpc.17.00371. Epub 2017 Oct 
      25.