PMID- 29072383
OWN - NLM
STAT- MEDLINE
DCOM- 20180808
LR  - 20220330
IS  - 0017-7768 (Print)
IS  - 0017-7768 (Linking)
VI  - 156
IP  - 10
DP  - 2017 Oct
TI  - [RESISTANCE OF HELICOBACTER PYLORI TO ANTIBIOTICS IN ISRAEL: PAST VS PRESENT].
PG  - 642-644
AB  - Helicobacter Pylori (H. Pylori) is a spiral shaped Gram-negative bacterium which 
      is known to cause chronic gastric inflammation (gastritis) that could develop 
      into a gastric or duodenal ulcer. The standard first line therapy for H. Pylori 
      infection is a 7-14 days period of "triple therapy" consisting of proton pump 
      inhibitors (PPI) and the antibiotics clarithromycin and amoxicillin or 
      metronidazole. Recently there has been an increase in H. Pylori resistance to 
      antibiotic treatment. Throughout the years 1999, 2002, 2010, 2013 and 2014 
      studies have been conducted in Israel that examined H. Pylori resistance rates 
      for commonly used antibiotics. These studies included 40-138 participants who 
      were diagnosed with infection caused by H. Pylori. Based on information derived 
      from these studies, there is a clear increase in H. Pylori resistance to 
      antibiotics, particularly to tetracycline, amoxicillin and clarithromycin.
FAU - Peretz, Avi
AU  - Peretz A
AD  - Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, affiliated 
      to the Faculty of Medicine, Bar Ilan University, Galilee, Israel.
FAU - Paritsky, Maya
AU  - Paritsky M
AD  - Gastrointestinal Unit, Baruch Padeh Medical Center, Poriya, affiliated to the 
      Faculty of Medicine, Bar Ilan University, Galilee, Israel.
FAU - Brodsky, Diana
AU  - Brodsky D
AD  - Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, affiliated 
      to the Faculty of Medicine, Bar Ilan University, Galilee, Israel.
FAU - Pastukh, Nina
AU  - Pastukh N
AD  - Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, affiliated 
      to the Faculty of Medicine, Bar Ilan University, Galilee, Israel.
FAU - On, Avi
AU  - On A
AD  - Pediatric Gastrointestinal Unit, Baruch Padeh Medical Center, Poriya, affiliated 
      to the Faculty of Medicine, Bar Ilan University, Galilee, Israel.
LA  - heb
PT  - Journal Article
PT  - Review
PL  - Israel
TA  - Harefuah
JT  - Harefuah
JID - 0034351
RN  - 0 (Anti-Bacterial Agents)
RN  - H1250JIK0A (Clarithromycin)
SB  - IM
MH  - Anti-Bacterial Agents/*therapeutic use
MH  - Clarithromycin
MH  - Colony Count, Microbial
MH  - *Drug Resistance, Bacterial
MH  - Drug Therapy, Combination
MH  - Helicobacter Infections/*drug therapy
MH  - Helicobacter pylori/*drug effects
MH  - Humans
MH  - Israel
MH  - Microbial Sensitivity Tests
EDAT- 2017/10/27 06:00
MHDA- 2018/08/09 06:00
CRDT- 2017/10/27 06:00
PHST- 2017/10/27 06:00 [entrez]
PHST- 2017/10/27 06:00 [pubmed]
PHST- 2018/08/09 06:00 [medline]
PST - ppublish
SO  - Harefuah. 2017 Oct;156(10):642-644.