PMID- 29072591 OWN - NLM STAT- MEDLINE DCOM- 20180416 LR - 20220408 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 14 IP - 11 DP - 2017 Oct 26 TI - Frequency of Loud Snoring and Metabolic Syndrome among Korean Adults: Results from the Health Examinees (HEXA) Study. LID - 10.3390/ijerph14111294 [doi] LID - 1294 AB - Studies regarding the association between snoring and metabolic abnormalities have been inconsistent. We examine whether snoring frequency and obstructive sleep apnea markers are associated with metabolic syndrome (MetS) among Koreans aged 40-69 years. A total of 72,885 subjects (24,856 men, 48,029 women) from the Health Examinees Gem study between 2009 and 2013 were included. Snoring frequency was grouped into five categories (never, 1-3/month, 1-3/week, 4-5/week, 6+/week). Obstructive sleep apnea markers included breathing interruptions and awakenings. Adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated through logistic regression. Compared with non-snorers, those who snore 6+/week were associated with increased odds for MetS (OR: 2.07, 95% CI: 1.91-2.25, p-trend < 0.0001 among men; OR: 1.45, CI: 1.33-1.58, p-trend < 0.0001 among women). Snoring frequency is associated with MetS and its components in both men and women. Snoring and obstructive sleep apnea markers are important indicators of sleep quality, which may facilitate early detection of sleep disorders and further complications such as MetS. FAU - Kim, Claire E AU - Kim CE AD - Department of Preventive Medicine, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. claireekim@snu.ac.kr. AD - Department of Biomedical Sciences, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. claireekim@snu.ac.kr. FAU - Shin, Sangah AU - Shin S AD - Department of Food and Nutrition, Chung-Ang University, Gyeonggi-do 17546, Korea. ssa8320@snu.ac.kr. FAU - Lee, Hwi-Won AU - Lee HW AD - Department of Preventive Medicine, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. hwiwon@snu.ac.kr. AD - Department of Biomedical Sciences, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. hwiwon@snu.ac.kr. FAU - Lim, Jiyeon AU - Lim J AD - Department of Preventive Medicine, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. jiyeonlim@snu.ac.kr. FAU - Lee, Jong-Koo AU - Lee JK AUID- ORCID: 0000-0003-4833-1178 AD - JW Lee Center for Global Medicine, College of Medicine, Seoul National University, IhwaJang-gil 71 Jongno-gu, Seoul 03087, Korea 03087. docmohw@snu.ac.kr. AD - Department of Family Medicine, Seoul National University Hospital, 101 Daehakro, Jongnogu, Seoul 03080, Korea. docmohw@snu.ac.kr. FAU - Kang, Daehee AU - Kang D AD - Department of Preventive Medicine, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. dhkang@snu.ac.kr. AD - Department of Biomedical Sciences, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea. dhkang@snu.ac.kr. AD - Institute of Environmental Medicine, Seoul National University Medical Research Center, 103 Daehakro, Jongnogu, Seoul 03080, Korea. dhkang@snu.ac.kr. LA - eng PT - Journal Article DEP - 20171026 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Adult MH - Aged MH - Female MH - Humans MH - Logistic Models MH - Male MH - Metabolic Syndrome/complications/*epidemiology MH - Middle Aged MH - Odds Ratio MH - Republic of Korea/epidemiology MH - Sleep Apnea, Obstructive/*epidemiology MH - Snoring/*epidemiology PMC - PMC5707933 OTO - NOTNLM OT - Korean OT - epidemiology OT - health examinees study OT - metabolic syndrome OT - snoring COIS- The authors declare no conflict of interest. EDAT- 2017/10/27 06:00 MHDA- 2018/04/17 06:00 PMCR- 2017/11/01 CRDT- 2017/10/27 06:00 PHST- 2017/09/14 00:00 [received] PHST- 2017/10/18 00:00 [revised] PHST- 2017/10/22 00:00 [accepted] PHST- 2017/10/27 06:00 [entrez] PHST- 2017/10/27 06:00 [pubmed] PHST- 2018/04/17 06:00 [medline] PHST- 2017/11/01 00:00 [pmc-release] AID - ijerph14111294 [pii] AID - ijerph-14-01294 [pii] AID - 10.3390/ijerph14111294 [doi] PST - epublish SO - Int J Environ Res Public Health. 2017 Oct 26;14(11):1294. doi: 10.3390/ijerph14111294.