PMID- 29075136 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1178-7090 (Print) IS - 1178-7090 (Electronic) IS - 1178-7090 (Linking) VI - 10 DP - 2017 TI - Outcomes of C1-2 joint injections. PG - 2263-2269 LID - 10.2147/JPR.S144255 [doi] AB - OBJECTIVE: Intra-articular injections of the C1-2 joint are an effective therapeutic option for pain generated from degenerative and inflammatory conditions affecting the joint. Limited information exists about the adverse events (AEs) associated with these injections. The primary aim of this study is to describe the frequency and type of AEs associated with C1-2 joint injections. The secondary aim is to identify clinical factors associated with the occurrence of AEs of C1-2 joint injections. DESIGN/METHODS: A retrospective chart review was conducted on all C1-2 joint injections performed at the Mayo Pain Medicine Clinic in Rochester, MN, from January 1, 2005 through July 31, 2015. AE data were extracted from procedural and post-procedural clinical notes. Analysis was conducted to determine correlations between any AE and demographic and clinical characteristics. Using univariate and multivariate logistic regression analyses, associations were determined. RESULTS: From January 1, 2005 to July 31, 2015, 135 C1-2 injections were performed on 72 patients. Overall, at least 1 AE was reported in 18.5% of the injections. The most common AEs were post-procedural increase in pain and procedural vascular contrast uptake. There was a significant association between AE occurrence and greater pre-procedural maximum pain score. CONCLUSIONS: AEs from C1-2 joint injections occurred commonly, but there were no persistent or serious AEs associated with these injections. The data also demonstrate that patients with higher pre-procedural maximum pain scores are more likely to experience an AE. FAU - Aiudi, Christopher M AU - Aiudi CM AD - Mayo Clinic School of Medicine. FAU - Hooten, W Michael AU - Hooten WM AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Sanders, Rebecca A AU - Sanders RA AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Watson, James C AU - Watson JC AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Moeschler, Susan M AU - Moeschler SM AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Gazelka, Halena M AU - Gazelka HM AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Hoelzer, Bryan C AU - Hoelzer BC AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Eldrige, Jason S AU - Eldrige JS AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. FAU - Qu, Wenchun AU - Qu W AD - Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA. FAU - Lamer, Tim J AU - Lamer TJ AD - Division of Pain Medicine, Department of Anesthesia and Perioperative Medicine, Mayo Clinic. LA - eng PT - Journal Article DEP - 20170918 PL - New Zealand TA - J Pain Res JT - Journal of pain research JID - 101540514 PMC - PMC5609790 OTO - NOTNLM OT - C1-2 joint OT - adverse event OT - facet OT - injection COIS- Disclosure The authors report no conflicts of interest in this work. EDAT- 2017/10/28 06:00 MHDA- 2017/10/28 06:01 PMCR- 2017/09/18 CRDT- 2017/10/28 06:00 PHST- 2017/10/28 06:00 [entrez] PHST- 2017/10/28 06:00 [pubmed] PHST- 2017/10/28 06:01 [medline] PHST- 2017/09/18 00:00 [pmc-release] AID - jpr-10-2263 [pii] AID - 10.2147/JPR.S144255 [doi] PST - epublish SO - J Pain Res. 2017 Sep 18;10:2263-2269. doi: 10.2147/JPR.S144255. eCollection 2017.