PMID- 29081458
OWN - NLM
STAT- MEDLINE
DCOM- 20180102
LR  - 20180102
IS  - 1882-1006 (Electronic)
IS  - 0015-6426 (Linking)
VI  - 58
IP  - 5
DP  - 2017
TI  - [Determination of Formetanate Hydrochloride in Agricultural Products by 
      LC-MS/MS].
PG  - 221-228
LID - 10.3358/shokueishi.58.221 [doi]
AB  - An analytical method based on LC-MS/MS was developed for the determination of 
      formetanate hydrochloride in agricultural products. Formetanate hydrochloride was 
      confirmed to be stable in acetonitrile. It was therefore extracted from samples 
      with acetonitrile, and the crude extracts were purified using a combination of 
      ethylenediamine-N-propyl silylation silica gel and graphite carbon mini columns. 
      Formetanate hydrochloride in the resulting sample solutions was quantified by 
      LC-MS/MS utilizing an external solvent calibration curve. The average recovery 
      (n=5) of formetanate hydrochloride spiked in 10 types of agricultural products 
      (brown rice, soybean, spinach, cabbage, potato, apple, orange, lime, nectarine 
      and green tea) at the maximum residue limits (MRLs) or at a uniform limit of 
      0.01 mg/kg was 92.3-103%, with a relative standard deviation of 1.3-5.4%. The 
      limit of quantitation of the developed method was calculated to be 0.01 mg/kg.
FAU - Kobayashi, Maki
AU  - Kobayashi M
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Sakai, Naoko
AU  - Sakai N
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Kamijo, Kyoko
AU  - Kamijo K
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Koike, Hiroshi
AU  - Koike H
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Nemoto, Satoru
AU  - Nemoto S
AD  - National Institute of Health Sciences.
FAU - Shindo, Tetsuya
AU  - Shindo T
AD  - Tokyo Metropolitan Institute of Public Health.
LA  - jpn
PT  - Journal Article
PL  - Japan
TA  - Shokuhin Eiseigaku Zasshi
JT  - Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan
JID - 0142214
RN  - 0 (Acetonitriles)
RN  - 0 (Carbamates)
RN  - 0 (Pesticide Residues)
RN  - 0 (Solutions)
RN  - 532HEC1KKM (formetanate)
RN  - Z072SB282N (acetonitrile)
SB  - IM
MH  - Acetonitriles
MH  - Carbamates/*analysis/isolation & purification
MH  - Chromatography, Liquid/*methods
MH  - Crops, Agricultural/*chemistry
MH  - Food Analysis/*methods
MH  - Pesticide Residues/*analysis
MH  - Solutions
MH  - Tandem Mass Spectrometry/*methods
OTO - NOTNLM
OT  - LC-MS/MS
OT  - agricultural products
OT  - formetanate hydrochloride
EDAT- 2017/10/31 06:00
MHDA- 2018/01/03 06:00
CRDT- 2017/10/31 06:00
PHST- 2017/10/31 06:00 [entrez]
PHST- 2017/10/31 06:00 [pubmed]
PHST- 2018/01/03 06:00 [medline]
AID - 10.3358/shokueishi.58.221 [doi]
PST - ppublish
SO  - Shokuhin Eiseigaku Zasshi. 2017;58(5):221-228. doi: 10.3358/shokueishi.58.221.