PMID- 29086538
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2233-6079 (Print)
IS  - 2233-6087 (Electronic)
IS  - 2233-6079 (Linking)
VI  - 41
IP  - 5
DP  - 2017 Oct
TI  - Features of Long-Standing Korean Type 2 Diabetes Mellitus Patients with Diabetic 
      Retinopathy: A Study Based on Standardized Clinical Data.
PG  - 393-404
LID - 10.4093/dmj.2017.41.5.393 [doi]
AB  - BACKGROUND: This is part of a prospective study carried out as a national project 
      to secure standardized public resources for type 2 diabetes mellitus (T2DM) 
      patients in Korea. We compared various characteristics of long-standing T2DM 
      patients with diabetic retinopathy (DR) and macular edema (ME). METHODS: From 
      September 2014 to July 2015, T2DM patients with disease duration of at least 15 
      years were recruited at a single university hospital. Clinical data and samples 
      were collected according to the common data elements and standards of procedure 
      developed by the Korean Diabetes Association Research Council. Each participant 
      was assessed by ophthalmologists for DR and ME. RESULTS: Among 220 registered 
      patients, 183 completed the ophthalmologic assessment. DR was associated with 
      longer disease duration (odds ratio [OR], 1.071; 95% confidence interval [CI], 
      1.001 to 1.147 for non-proliferative diabetic retinopathy [NPDR]) (OR, 1.142; 95% 
      CI, 1.051 to 1.242 for proliferative diabetic retinopathy [PDR]) and the use of 
      long-acting insulin (OR, 4.559; 95% CI, 1.672 to 12.427 for NPDR) (OR, 4.783; 95% 
      CI, 1.581 to 14.474 for PDR), but a lower prevalence of a family history of 
      cancer (OR, 0.310; 95% CI, 0.119 to 0.809 for NPDR) (OR, 0.206; 95% CI, 0.063 to 
      0.673 for PDR). ME was associated with higher glycosylated hemoglobin levels (OR, 
      1.380; 95% CI, 1.032 to 1.845) and the use of rapid-acting insulin (OR, 5.211; 
      95% CI, 1.445 to 18.794). CONCLUSION: Various clinical features were associated 
      with DR and ME. Additional epidemiological and biorepository-based studies using 
      this cohort are being conducted to deepen our understanding of diabetic 
      complications in Korea.
CI  - Copyright (c) 2017 Korean Diabetes Association
FAU - Park, Sejeong
AU  - Park S
AD  - Department of Endocrinology and Metabolism, Kyung Hee University School of 
      Medicine, Seoul, Korea.
FAU - Rhee, Sang Youl
AU  - Rhee SY
AD  - Department of Endocrinology and Metabolism, Kyung Hee University School of 
      Medicine, Seoul, Korea.
FAU - Jeong, Su Jin
AU  - Jeong SJ
AD  - Statistics Support Department, Medical Science Research Institute, Kyung Hee 
      University Medical Center, Kyung Hee University School of Medicine, Seoul, Korea.
FAU - Kim, Kiyoung
AU  - Kim K
AD  - Department of Ophthalmology, Kyung Hee University School of Medicine, Seoul, 
      Korea.
FAU - Chon, Suk
AU  - Chon S
AD  - Department of Endocrinology and Metabolism, Kyung Hee University School of 
      Medicine, Seoul, Korea.
FAU - Yu, Seung Young
AU  - Yu SY
AD  - Department of Ophthalmology, Kyung Hee University School of Medicine, Seoul, 
      Korea.
FAU - Woo, Jeong Taek
AU  - Woo JT
AUID- ORCID: 0000-0001-9201-0713
AD  - Department of Endocrinology and Metabolism, Kyung Hee University School of 
      Medicine, Seoul, Korea. jtwoomd@khmc.or.kr.
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - Diabetes Metab J
JT  - Diabetes & metabolism journal
JID - 101556588
CIN - Diabetes Metab J. 2017 Dec;41(6):492-493. PMID: 29272084
PMC - PMC5663679
OTO - NOTNLM
OT  - Diabetes complications
OT  - Diabetes mellitus, type 2
OT  - Diabetic retinopathy
OT  - Macular edema
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2017/11/01 06:00
MHDA- 2017/11/01 06:01
PMCR- 2017/10/01
CRDT- 2017/11/01 06:00
PHST- 2017/01/25 00:00 [received]
PHST- 2017/06/05 00:00 [accepted]
PHST- 2017/11/01 06:00 [entrez]
PHST- 2017/11/01 06:00 [pubmed]
PHST- 2017/11/01 06:01 [medline]
PHST- 2017/10/01 00:00 [pmc-release]
AID - 41.393 [pii]
AID - 10.4093/dmj.2017.41.5.393 [doi]
PST - ppublish
SO  - Diabetes Metab J. 2017 Oct;41(5):393-404. doi: 10.4093/dmj.2017.41.5.393.