PMID- 29089913 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1664-1078 (Print) IS - 1664-1078 (Electronic) IS - 1664-1078 (Linking) VI - 8 DP - 2017 TI - Diabetes-Related Distress and Depressive Symptoms Are Not Merely Negative over a 3-Year Period in Malaysian Adults with Type 2 Diabetes Mellitus Receiving Regular Primary Diabetes Care. PG - 1834 LID - 10.3389/fpsyg.2017.01834 [doi] LID - 1834 AB - For people with type 2 diabetes mellitus (T2DM) the daily maintenance of physical and psychological health is challenging. However, the interrelatedness of these two health domains, and of diabetes-related distress (DRD) and depressive symptoms, in the Asian population is still poorly understood. DRD and depressive symptoms have important but distinct influences on diabetes self-care and disease control. Furthermore, the question of whether changes in DRD or depressive symptoms follow a more or less natural course or depend on disease and therapy-related factors is yet to be answered. The aim of this study was to identify the factors influencing changes in DRD or depressive symptoms, at a 3-year follow-up point, in Malaysian adults with T2DM who received regular primary diabetes care. Baseline data included age, sex, ethnicity, marital status, educational level, employment status, health-related quality of life (WHOQOL-BREF), insulin use, diabetes-related complications and HbA1c. DRD was assessed both at baseline and after 3 years using a 17-item Diabetes Distress Scale (DDS-17), while depressive symptoms were assessed using the Patient Health Questionnaire (PHQ-9). Linear mixed models were used to examine the relationship between baseline variables and change scores in DDS-17 and PHQ-9. Almost half (336) of 700 participants completed both measurements. At follow-up, their mean (SD) age and diabetes duration were 60.6 (10.1) years and 9.8 (5.9) years, respectively, and 54.8% were women. More symptoms of depression at baseline was the only significant and independent predictor of improved DRD at 3 years (adjusted beta = -0.06, p = 0.002). Similarly, worse DRD at baseline was the only significant and independent predictor of fewer depressive symptoms 3 years later (adjusted beta = -0.98, p = 0.005). Thus, more "negative feelings" at baseline could be a manifestation of initial coping behaviors or a facilitator of a better psychological coaching by physicians or nurses that might be beneficial in the long term. We therefore conclude that initial negative feelings should not be seen as a necessarily adverse factor in diabetes care. FAU - Chew, Boon-How AU - Chew BH AD - Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia. AD - Department of General Practice, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands. FAU - Vos, Rimke C AU - Vos RC AD - Department of General Practice, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands. FAU - Stellato, Rebecca K AU - Stellato RK AD - Department of General Practice, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands. FAU - Rutten, Guy E H M AU - Rutten GEHM AD - Department of General Practice, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands. LA - eng PT - Journal Article DEP - 20171017 PL - Switzerland TA - Front Psychol JT - Frontiers in psychology JID - 101550902 PMC - PMC5651035 OTO - NOTNLM OT - HbA1c OT - NCT02730754 OT - complications OT - depression OT - diabetes distress OT - https://clinicaltrials.gov/ct2/show/NCT02730754. OT - primary care OT - quality of life OT - type 2 diabetes mellitus EDAT- 2017/11/02 06:00 MHDA- 2017/11/02 06:01 PMCR- 2017/10/17 CRDT- 2017/11/02 06:00 PHST- 2017/05/12 00:00 [received] PHST- 2017/10/02 00:00 [accepted] PHST- 2017/11/02 06:00 [entrez] PHST- 2017/11/02 06:00 [pubmed] PHST- 2017/11/02 06:01 [medline] PHST- 2017/10/17 00:00 [pmc-release] AID - 10.3389/fpsyg.2017.01834 [doi] PST - epublish SO - Front Psychol. 2017 Oct 17;8:1834. doi: 10.3389/fpsyg.2017.01834. eCollection 2017.