PMID- 29091109 OWN - NLM STAT- MEDLINE DCOM- 20180530 LR - 20180530 IS - 1678-2690 (Electronic) IS - 0001-3765 (Linking) VI - 89 IP - 3 Suppl DP - 2017 TI - Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM. PG - 2411-2422 LID - 10.1590/0001-3765201720170230 [doi] AB - In this work, the physicochemical and blood compatibility properties of prepared PU/Bio oil nanocomposites were investigated. Scanning electron microscope (SEM) studies revealed the reduction of mean fiber diameter (709 +/- 211 nm) compared to the pristine PU (969 nm +/- 217 nm). Fourier transform infrared spectroscopy (FTIR) analysis exposed the characteristic peaks of pristine PU. Composite peak intensities were decreased insinuating the interaction of the bio oilTM with the PU. Contact angle analysis portrayed the hydrophobic nature of the fabricated patch compared to pristine PU. Thermal gravimetric analysis (TGA) depicted the better thermal stability of the novel nanocomposite patch and its different thermal behavior in contrast with the pristine PU. Atomic force microscopy (AFM) analysis revealed the increase in the surface roughness of the composite patch. Activated partial thromboplastin time (APTT) and prothrombin time (PT) signified the novel nanocomposite patch ability in reducing the thrombogenicity and promoting the anticoagulant nature. Finally the hemolytic percentage of the fabricated composite was in the acceptable range revealing its safety and compatibility with the red blood cells. To reinstate, the fabricated patch renders promising physicochemical and blood compatible nature making it a new putative candidate for wound healing application. FAU - Ayyar, Manikandan AU - Ayyar M AD - Department of Chemistry, Bharath University, Chennai 600073, Tamil Nadu, India. FAU - Mani, Mohan Prasath AU - Mani MP AD - Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor Bahru, Malaysia. FAU - Jaganathan, Saravana Kumar AU - Jaganathan SK AD - Department for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City, Vietnam. AD - Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam. AD - IJNUTM Cardiovascular Engineering Centre, Department of Clinical Sciences, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor Bahru, Malaysia. FAU - Rathinasamy, Rajasekar AU - Rathinasamy R AD - Department of Mechanical Engineering, Kongu Engineering college, Perunduari 638052, Tamil Nadu, India. FAU - Khudzari, Ahmad Zahran AU - Khudzari AZ AD - IJNUTM Cardiovascular Engineering Centre, Department of Clinical Sciences, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor Bahru, Malaysia. FAU - Krishnasamy, Navaneetha Pandiyaraj AU - Krishnasamy NP AD - Department of Physics, Sri Sakthi Institute of Engineering and Technology, Coimbatore 641062, Tamil Nadu, India. LA - eng PT - Journal Article DEP - 20171026 PL - Brazil TA - An Acad Bras Cienc JT - Anais da Academia Brasileira de Ciencias JID - 7503280 RN - 0 (Membranes, Artificial) RN - 0 (Polyurethanes) SB - IM MH - Humans MH - *Materials Testing MH - *Membranes, Artificial MH - Microscopy, Electron, Scanning MH - Nanocomposites/chemistry/*ultrastructure MH - Polyurethanes/*chemistry MH - Spectroscopy, Fourier Transform Infrared MH - Surface Properties EDAT- 2017/11/02 06:00 MHDA- 2018/05/31 06:00 CRDT- 2017/11/02 06:00 PHST- 2017/03/27 00:00 [received] PHST- 2017/06/12 00:00 [accepted] PHST- 2017/11/02 06:00 [pubmed] PHST- 2018/05/31 06:00 [medline] PHST- 2017/11/02 06:00 [entrez] AID - S0001-37652017005025104 [pii] AID - 10.1590/0001-3765201720170230 [doi] PST - ppublish SO - An Acad Bras Cienc. 2017;89(3 Suppl):2411-2422. doi: 10.1590/0001-3765201720170230. Epub 2017 Oct 26.