PMID- 2909322 OWN - NLM STAT- MEDLINE DCOM- 19890201 LR - 20190706 IS - 0090-3493 (Print) IS - 0090-3493 (Linking) VI - 17 IP - 1 DP - 1989 Jan TI - Noninvasive assessment of cardiac output by impedance cardiography in the newborn canine. PG - 63-5 AB - Currently, critical care monitoring of cardiac function in the newborn human consists mainly of measuring heart rate and BP. A noninvasive technique for assessing cardiac output routinely in the critically ill neonate would facilitate clinical management. Impedance cardiography (IC) is a noninvasive technique which measures stroke volume on a beat-by-beat basis. This study compared cardiac output as measured by thermodilution (TD) to that measured by IC in seven canine pups 6 to 7 days old weighing 0.66 to 0.86 kg. Cardiac output was altered by the withdrawal and reinfusion of blood. There were no significant differences between the two methods for either the absolute value of cardiac output (r = .96) or the percent change in cardiac output (r = .97). Coefficients of variation were 3.0% for TD and 3.6% for IC. These results indicate that IC can be used to assess serially cardiac function in the newborn. FAU - Gotshall, R W AU - Gotshall RW AD - Department of Physiology and Biophysics, Wright State University School of Medicine, Dayton, OH 45401-0927. FAU - Miles, D S AU - Miles DS LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Crit Care Med JT - Critical care medicine JID - 0355501 SB - IM MH - Animals MH - Animals, Newborn/*physiology MH - *Cardiac Output MH - *Cardiography, Impedance MH - Dogs MH - Models, Biological MH - *Plethysmography, Impedance MH - Stroke Volume MH - *Thermodilution EDAT- 1989/01/01 00:00 MHDA- 1989/01/01 00:01 CRDT- 1989/01/01 00:00 PHST- 1989/01/01 00:00 [pubmed] PHST- 1989/01/01 00:01 [medline] PHST- 1989/01/01 00:00 [entrez] AID - 10.1097/00003246-198901000-00013 [doi] PST - ppublish SO - Crit Care Med. 1989 Jan;17(1):63-5. doi: 10.1097/00003246-198901000-00013.