PMID- 29094807
OWN - NLM
STAT- MEDLINE
DCOM- 20190125
LR  - 20190125
IS  - 1468-1293 (Electronic)
IS  - 1464-2662 (Linking)
VI  - 19
IP  - 2
DP  - 2018 Feb
TI  - Food insecurity may lead to incomplete HIV viral suppression and less immune 
      reconstitution among HIV/hepatitis C virus-coinfected people.
PG  - 123-131
LID - 10.1111/hiv.12561 [doi]
AB  - OBJECTIVES: The aim of this study was to determine the impact of food insecurity 
      (FI) on HIV viral load and CD4 count among people coinfected with HIV and 
      hepatitis C virus (HCV). METHODS: This study was conducted using data from the 
      Food Security & HIV-HCV Sub-Study of the Canadian Co-Infection Cohort study. FI 
      was measured using the adult scale of Health Canada's Household Food Security 
      Survey Module and was classified into three categories: food security, moderate 
      food insecurity and severe food insecurity. The association between FI, HIV viral 
      load, and CD4 count was assessed using a stabilized inverse probability weighted 
      marginal structural model. RESULTS: A total of 725 HIV/HCV-coinfected people with 
      1973 person-visits over 3 years of follow-up contributed to this study. At 
      baseline, 23% of participants experienced moderate food insecurity and 34% 
      experienced severe food insecurity. The proportion of people with undetectable 
      HIV viral load was 75% and the median CD4 count was 460 [interquartile range 
      (IQR): 300-665] cells/muL. People experiencing severe food insecurity had 1.47 
      times [95% confidence interval (CI): 1.14, 1.88] the risk of having detectable 
      HIV viral load and a 0.91-fold (95% CI: 0.84, 0.98) increase in CD4 count 
      compared with people who were food secure. CONCLUSIONS: These findings provide 
      evidence of the negative impact of food insecurity on HIV viral load and CD4 
      count among HIV/HCV-coinfected people.
CI  - (c) 2017 British HIV Association.
FAU - Aibibula, W
AU  - Aibibula W
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
FAU - Cox, J
AU  - Cox J
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
AD  - Department of Medicine, McGill University, Montreal, QC, Canada.
FAU - Hamelin, A-M
AU  - Hamelin AM
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
FAU - Moodie, Eem
AU  - Moodie E
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
FAU - Naimi, A I
AU  - Naimi AI
AD  - Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
FAU - McLinden, T
AU  - McLinden T
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
FAU - Klein, M B
AU  - Klein MB
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
AD  - Department of Medicine, McGill University, Montreal, QC, Canada.
FAU - Brassard, P
AU  - Brassard P
AD  - Department of Epidemiology, Biostatistics and Occupational Health, McGill 
      University, Montreal, QC, Canada.
AD  - Department of Medicine, McGill University, Montreal, QC, Canada.
AD  - Center for Clinical Epidemiology, Jewish General Hospital, Montreal, QC, Canada.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171102
PL  - England
TA  - HIV Med
JT  - HIV medicine
JID - 100897392
SB  - IM
MH  - Adult
MH  - CD4 Lymphocyte Count
MH  - Canada
MH  - Cohort Studies
MH  - Coinfection/*drug therapy
MH  - Female
MH  - *Food Supply
MH  - HIV Infections/*complications/*drug therapy
MH  - Hepatitis C, Chronic/*complications
MH  - Humans
MH  - *Immune Reconstitution
MH  - Male
MH  - Middle Aged
MH  - *Sustained Virologic Response
MH  - Treatment Outcome
MH  - Viral Load
OTO - NOTNLM
OT  - CD4 count
OT  - HIV viral load
OT  - HIV/HCV coinfection
OT  - food insecurity
OT  - marginal structural model
EDAT- 2017/11/03 06:00
MHDA- 2019/01/27 06:00
CRDT- 2017/11/03 06:00
PHST- 2017/09/15 00:00 [accepted]
PHST- 2017/11/03 06:00 [pubmed]
PHST- 2019/01/27 06:00 [medline]
PHST- 2017/11/03 06:00 [entrez]
AID - 10.1111/hiv.12561 [doi]
PST - ppublish
SO  - HIV Med. 2018 Feb;19(2):123-131. doi: 10.1111/hiv.12561. Epub 2017 Nov 2.