PMID- 29098333
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180110
LR  - 20180710
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 410
IP  - 1
DP  - 2018 Jan
TI  - Synthesis of multirecognition magnetic molecularly imprinted polymer by atom 
      transfer radical polymerization and its application in magnetic solid-phase 
      extraction.
PG  - 247-257
LID - 10.1007/s00216-017-0716-9 [doi]
AB  - In this work, we reported an effective method for the synthesis of a 
      multirecognition magnetic molecularly imprinted polymer (MMIP) with atom transfer 
      radical polymerization (ATRP), using 2,4-diamino-6-methyl-1,3,5-triazine as 
      pseudo-template. The resulting MMIP was characterized in detail by Fourier 
      transform-infrared (FT-IR) spectra, scanning electron microscopy (SEM), 
      thermogravimetic analysis (TGA), and vibrating sample magnetometry (VSM). These 
      results indicated the successful synthesis of MMIP with sufficient thermal 
      stability and magnetic properties. The adsorption experiments were carried out to 
      evaluate the specific selectivity of MMIP related to the spatial structure of 
      target molecules. The MMIP exhibited multirecognition ability and excellent 
      binding capability for melamine (MEL), cyromazine (CYR), triamterene (TAT), 
      diaveridine (DVD), and trimethoprim (TME), and the apparent maximum number of 
      binding sites (Q (max)) was 77.5, 75.2, 72.5, 69.9, and 70.4 mumol g(-1), 
      respectively. The multirecognition MMIP not only possessed adequate magnetic 
      responsiveness for fast separation but also avoided the risk of template leakage 
      on trace component analysis. Therefore, it was suitable for serving as a magnetic 
      solid-phase extraction (MSPE) adsorbent. MSPE coupled with high-performance 
      liquid chromatography analysis was applied to enrich and separate five target 
      molecules from three samples. Recoveries for all target molecules ranged from 
      81.6 to 91.5% with relative standard deviations of no more than 4.1% (n = 3). 
      Graphical abstract Multirecognition property of magnetic molecularly imprinted 
      polymer prepared with pseudo template.
FAU - Kong, Xiang-Jin
AU  - Kong XJ
AD  - School of Chemistry and Chemical Engineering, Liaocheng University, Dongchangfu 
      District, Liaocheng, Shandong, 252059, China.
FAU - Zheng, Chao
AU  - Zheng C
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Lan, Yao-Han
AU  - Lan YH
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Chi, Shuai-Shuai
AU  - Chi SS
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Dong, Qian
AU  - Dong Q
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Liu, Hao-Long
AU  - Liu HL
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Peng, Chao
AU  - Peng C
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Dong, Lin-Yi
AU  - Dong LY
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
FAU - Xu, Liang
AU  - Xu L
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China.
AD  - Tianjin Medical College, 14 Liulin Road, Hexi District, Tianjin, 300222, China.
FAU - Wang, Xian-Hua
AU  - Wang XH
AD  - Tianjin Key Laboratory on Technologies Enabling Development of Clinical 
      Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 22 
      Qixiangtai Road, Heping District, Tianjin, 300070, China. xianhua.w@163.com.
LA  - eng
GR  - 21605114/National Natural Science Foundation of China/
GR  - 2015T80226/China Postdoctoral Science Foundation/
GR  - 16JCQNJC05500/Natural Science Foundation of Tianjin City/
GR  - 201610062011/National Student's Platform for Innovation and Entrepreneurship 
      Training Program/
PT  - Journal Article
DEP - 20171102
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
OTO - NOTNLM
OT  - Atom transfer radical polymerization
OT  - Magnetic molecularly imprinted polymer
OT  - Magnetic solid-phase extraction
OT  - Multirecognition
EDAT- 2017/11/04 06:00
MHDA- 2017/11/04 06:01
CRDT- 2017/11/04 06:00
PHST- 2017/09/14 00:00 [received]
PHST- 2017/10/17 00:00 [accepted]
PHST- 2017/11/04 06:00 [pubmed]
PHST- 2017/11/04 06:01 [medline]
PHST- 2017/11/04 06:00 [entrez]
AID - 10.1007/s00216-017-0716-9 [pii]
AID - 10.1007/s00216-017-0716-9 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2018 Jan;410(1):247-257. doi: 10.1007/s00216-017-0716-9. Epub 
      2017 Nov 2.