PMID- 29098478
OWN - NLM
STAT- MEDLINE
DCOM- 20180209
LR  - 20181202
IS  - 1539-0829 (Electronic)
IS  - 1534-4827 (Linking)
VI  - 17
IP  - 12
DP  - 2017 Nov 2
TI  - Persistent Organic Pollutants as Risk Factors for Obesity and Diabetes.
PG  - 132
LID - 10.1007/s11892-017-0966-0 [doi]
AB  - PURPOSE OF REVIEW: The rising prevalence of obesity and diabetes cannot be fully 
      explained by known risk factors, such as unhealthy diet, a sedentary lifestyle, 
      and family history. This review summarizes the available studies linking 
      persistent organic pollutants (POPs) to obesity and diabetes and discusses 
      plausible underlying mechanisms. RECENT FINDINGS: Increasing evidence suggest 
      that POPs may act as obesogens and diabetogens to promote the development of 
      obesity and diabetes and induce metabolic dysfunction. POPs are synthesized 
      chemicals and are used widely in our daily life. These chemicals are resistant to 
      degradation in chemical or biological processes, which enable them to exist in 
      the environment persistently and to be bio-accumulated in animal and human tissue 
      through the food chain. Increasingly, epidemiologic studies suggest a positive 
      association between POPs and risk of developing diabetes. Understanding the 
      relationship of POPs with obesity and diabetes may shed light on preventive 
      strategies for obesity and diabetes.
FAU - Yang, Chunxue
AU  - Yang C
AD  - Partner, State Key Laboratory of Environmental and Biological Analysis, and 
      Department of Chemistry, Hong Kong Baptist University, 224, Waterloo Road, 
      Kowloon Tong, Hong Kong, China.
FAU - Kong, Alice Pik Shan
AU  - Kong APS
AD  - Department of Medicine and Therapeutics, The Chinese University of Hong Kong, 
      Prince of Wales Hospital, Hong Kong, SAR, China.
AD  - Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, 
      Prince of Wales Hospital, Hong Kong, SAR, China.
AD  - Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, 
      Prince of Wales Hospital, Hong Kong, SAR, China.
FAU - Cai, Zongwei
AU  - Cai Z
AD  - Partner, State Key Laboratory of Environmental and Biological Analysis, and 
      Department of Chemistry, Hong Kong Baptist University, 224, Waterloo Road, 
      Kowloon Tong, Hong Kong, China. zwcai@hkbu.edu.hk.
AD  - HKBU Institute for Research and Continuing Education, Shenzhen, China. 
      zwcai@hkbu.edu.hk.
FAU - Chung, Arthur C K
AU  - Chung ACK
AD  - Partner, State Key Laboratory of Environmental and Biological Analysis, and 
      Department of Chemistry, Hong Kong Baptist University, 224, Waterloo Road, 
      Kowloon Tong, Hong Kong, China. chungack@hkbu.edu.hk.
AD  - HKBU Institute for Research and Continuing Education, Shenzhen, China. 
      chungack@hkbu.edu.hk.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20171102
PL  - United States
TA  - Curr Diab Rep
JT  - Current diabetes reports
JID - 101093791
RN  - 0 (Environmental Pollutants)
RN  - 0 (Organic Chemicals)
SB  - IM
MH  - Animals
MH  - Diabetes Mellitus/*chemically induced/*epidemiology
MH  - Environmental Pollutants/*adverse effects
MH  - Humans
MH  - Obesity/*chemically induced/*epidemiology
MH  - Organic Chemicals/*adverse effects
MH  - Risk Factors
OTO - NOTNLM
OT  - diabetes
OT  - metabolic diseases
OT  - obesity
OT  - persistent organic pollutants
EDAT- 2017/11/04 06:00
MHDA- 2018/02/10 06:00
CRDT- 2017/11/04 06:00
PHST- 2017/11/04 06:00 [entrez]
PHST- 2017/11/04 06:00 [pubmed]
PHST- 2018/02/10 06:00 [medline]
AID - 10.1007/s11892-017-0966-0 [pii]
AID - 10.1007/s11892-017-0966-0 [doi]
PST - epublish
SO  - Curr Diab Rep. 2017 Nov 2;17(12):132. doi: 10.1007/s11892-017-0966-0.