PMID- 29099078
OWN - NLM
STAT- MEDLINE
DCOM- 20180608
LR  - 20181207
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 22
IP  - 11
DP  - 2017 Nov 2
TI  - Fast Extraction and Detection of 4-Methylimidazole in Soy Sauce Using Magnetic 
      Molecularly Imprinted Polymer by HPLC.
LID - 10.3390/molecules22111885 [doi]
LID - 1885
AB  - On the basis of magnetic molecularly imprinted polymer (MMIP) solid-phase 
      extraction coupled with high performance liquid chromatography, we established a 
      new method for the determination of the 4-methylimidazole (4-MEI) in soy sauce. 
      Scanning electron microscopy (SEM), Fourier transform infrared (FT-IR), X-ray 
      diffraction (XRD) and vibrating sample magnetometer (VSM) were used to 
      characterize the synthesized MMIPs. To evaluate the polymers, batch rebinding 
      experiments were carried out. The binding strength and capacity were determined 
      from the derived Freundlich isotherm (FI) equation. The selective recognition 
      capability of MMIPs was investigated with a reference compound and a structurally 
      similar compound. As a selective pre-concentration sorbents for 4-methylimidazole 
      in soy sauce, the MMIPs showed a satisfied recoveries rate of spiked samples, 
      ranged from 97% to 105%. As a result, the prepared MMIPs could be applied to 
      selectively pre-concentrate and determine 4-methylimidazole in soy sauce samples.
FAU - Feng, Zufei
AU  - Feng Z
AD  - Department of Applied Chemistry, School of Science, Xi'an University of 
      Technology, Xi'an 710061, China. zufeifeng@xaut.edu.cn.
FAU - Lu, Yan
AU  - Lu Y
AD  - Department of Applied Chemistry, School of Science, Xi'an University of 
      Technology, Xi'an 710061, China. 18829039398@163.com.
FAU - Zhao, Yingjuan
AU  - Zhao Y
AD  - Department of Applied Chemistry, School of Science, Xi'an University of 
      Technology, Xi'an 710061, China. zhaoyj@xaut.edu.cn.
FAU - Ye, Helin
AU  - Ye H
AD  - School of Chemistry and Environmental Science, Lanzhou City University, Lanzhou 
      730070, China. yehelin82@163.com.
LA  - eng
PT  - Journal Article
DEP - 20171102
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Imidazoles)
RN  - 0 (Magnetite Nanoparticles)
RN  - Q64GF9FV4I (4-methylimidazole)
SB  - IM
MH  - Chromatography, High Pressure Liquid/instrumentation/*methods
MH  - Food Analysis/methods
MH  - Imidazoles/*analysis/*isolation & purification
MH  - Magnetics
MH  - Magnetite Nanoparticles/chemistry
MH  - Molecular Imprinting/methods
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/*methods
MH  - Soy Foods/*analysis
MH  - Spectroscopy, Fourier Transform Infrared
MH  - X-Ray Diffraction
PMC - PMC6150302
OTO - NOTNLM
OT  - 4-methylimidazole
OT  - high performance liquid chromatography
OT  - magnetic molecularly imprinted polymer
OT  - soy sauce samples
COIS- The authors declare no conflict of interest.
EDAT- 2017/11/04 06:00
MHDA- 2018/06/09 06:00
PMCR- 2017/11/02
CRDT- 2017/11/04 06:00
PHST- 2017/09/29 00:00 [received]
PHST- 2017/10/31 00:00 [revised]
PHST- 2017/11/01 00:00 [accepted]
PHST- 2017/11/04 06:00 [entrez]
PHST- 2017/11/04 06:00 [pubmed]
PHST- 2018/06/09 06:00 [medline]
PHST- 2017/11/02 00:00 [pmc-release]
AID - molecules22111885 [pii]
AID - molecules-22-01885 [pii]
AID - 10.3390/molecules22111885 [doi]
PST - epublish
SO  - Molecules. 2017 Nov 2;22(11):1885. doi: 10.3390/molecules22111885.