PMID- 2909918
OWN - NLM
STAT- MEDLINE
DCOM- 19890209
LR  - 20190514
IS  - 0028-3878 (Print)
IS  - 0028-3878 (Linking)
VI  - 39
IP  - 1
DP  - 1989 Jan
TI  - The rostral basilar artery syndrome: diagnosis, etiology, prognosis.
PG  - 9-16
AB  - Vascular occlusive disease of the rostral basilar artery (RBAS) causes a myriad 
      of clinical signs and symptoms reflecting rostral brainstem-diencephalic and 
      posterior hemispheric dysfunction. To help define the clinical profile, we 
      prospectively studied 61 patients with clinical/neuroimaging evidence of RBAS 
      during a 7-year period. Fourteen patients mirrored classic descriptions: severe 
      visual, oculomotor and behavioral signs without prominent motoric dysfunction, 
      uniformly poor prognosis, and intimate association with hypertension and prior 
      episodes of vertebrobasilar ischemia (VBI). In contrast, 47 individuals had a 
      reversible syndrome with excellent short-term functional recoveries, and were 
      distinguished by a lower frequency and severity of hypertension, a greater 
      incidence of arrhythmias in the young, and no history of VBI. All patients had 
      important neurobehavioral abnormalities including an invariable acute confusional 
      state. Diagnosis required the integrated assessment of neurobehavioral, 
      ophthalmologic, and imaging tests. The clinical syndrome is more common and 
      etiologically diverse than previously reported and is frequently unrecognized in 
      the young and elderly who present with acute confusion.
FAU - Mehler, M F
AU  - Mehler MF
AD  - Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, NY 
      10461.
LA  - eng
GR  - U10 NS086531/NS/NINDS NIH HHS/United States
GR  - NS00856/NS/NINDS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Neurology
JT  - Neurology
JID - 0401060
SB  - IM
MH  - Adult
MH  - Aged
MH  - Behavior
MH  - Cerebral Angiography
MH  - Cerebrovascular Disorders/complications
MH  - Eye Diseases/etiology
MH  - Humans
MH  - Middle Aged
MH  - Nervous System Diseases/etiology
MH  - Prospective Studies
MH  - Syndrome
MH  - Tomography, X-Ray Computed
MH  - Vertebrobasilar Insufficiency/complications/*diagnostic imaging/etiology
EDAT- 1989/01/01 00:00
MHDA- 1989/01/01 00:01
CRDT- 1989/01/01 00:00
PHST- 1989/01/01 00:00 [pubmed]
PHST- 1989/01/01 00:01 [medline]
PHST- 1989/01/01 00:00 [entrez]
AID - 10.1212/wnl.39.1.9 [doi]
PST - ppublish
SO  - Neurology. 1989 Jan;39(1):9-16. doi: 10.1212/wnl.39.1.9.