PMID- 29099635
OWN - NLM
STAT- MEDLINE
DCOM- 20180724
LR  - 20220410
IS  - 1541-2563 (Electronic)
IS  - 1541-2563 (Linking)
VI  - 14
IP  - 6
DP  - 2017 Dec
TI  - Nutritional Status of Patients with Chronic Obstructive Pulmonary Disease in 
      Relation to their Physical Performance.
PG  - 626-634
LID - 10.1080/15412555.2017.1386643 [doi]
AB  - Nutritional abnormalities and physical inactivity are highly prevalent in 
      patients with chronic obstructive pulmonary disease (COPD). The aim of this study 
      was to determine the association between nutritional status/body composition and 
      physical performance in patients with COPD. A cross-sectional observational study 
      was conducted in outpatients with clinically stable, moderate to very severe 
      COPD. In the assessment of nutritional status, we used dual energy X-ray 
      absorptiometry, anthropometry, serum biomarkers, and the Mini-Nutritional 
      Assessment (MNA) questionnaire. Physical performance was measured by the 6-minute 
      walk distance (6MWD), 4-metre gait speed (4MGS), and physical activity. 
      Univariate and multivariate analyses were performed. In 111 patients (mean age 
      68 years, 69% men), the mean 6MWD was 376 +/- 119 m, 4MGS 0.9 +/- 0.2 m/s, and the 
      average daily step count 8,059 +/- 4,757. Patients with low exercise capacity (6MWD 
      </= 350 m) had a significantly lower lean mass index (LMI) (p < 0.01), fat-free 
      mass index (FFMI) (p < 0.01), bone mineral content (p < 0.01), bone mineral 
      density (p < 0.01), T-score (p < 0.05), MNA score (p < 0.01), and serum albumin 
      and prealbumin levels (p < 0.05). Patients with low physical activity (daily step 
      count </= median) had lower LMI, FFMI, MNA score, serum prealbumin (for all 
      comparisons p < 0.05) and vitamin D levels (p < 0.01). However, none of the 
      nutritional variables showed an independent association with low physical 
      performance in the multivariate models. In conclusion, patients with low physical 
      performance have deficient nutritional status, but we could not demonstrate an 
      independent relationship between nutritional parameters and physical performance.
FAU - Matkovic, Zinka
AU  - Matkovic Z
AD  - a Department of Internal Medicine, Division of Pulmonary Medicine , Dubrava 
      University Hospital , Zagreb , Croatia.
FAU - Cvetko, Danijel
AU  - Cvetko D
AD  - b Department of Diagnostic and Interventional Radiology , Dubrava University 
      Hospital , Zagreb , Croatia.
FAU - Rahelic, Dario
AU  - Rahelic D
AD  - c Department of Endocrinology, Diabetes and Metabolic Disorders , Dubrava 
      University Hospital , Zagreb , Croatia.
FAU - Esquinas, Cristina
AU  - Esquinas C
AD  - d Pneumology Department , Hospital Universitari Vall d'Hebron , Barcelona , 
      Spain.
FAU - Zarak, Marko
AU  - Zarak M
AD  - e Department of Laboratory Diagnostics , Dubrava University Hospital , Zagreb , 
      Croatia.
FAU - Miravitlles, Marc
AU  - Miravitlles M
AUID- ORCID: 0000-0002-9850-9520
AD  - d Pneumology Department , Hospital Universitari Vall d'Hebron , Barcelona , 
      Spain.
FAU - Tudoric, Neven
AU  - Tudoric N
AD  - a Department of Internal Medicine, Division of Pulmonary Medicine , Dubrava 
      University Hospital , Zagreb , Croatia.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20171103
PL  - England
TA  - COPD
JT  - COPD
JID - 101211769
RN  - 0 (Prealbumin)
RN  - 1406-16-2 (Vitamin D)
SB  - IM
MH  - Absorptiometry, Photon
MH  - *Activities of Daily Living
MH  - Adipose Tissue/diagnostic imaging
MH  - Aged
MH  - *Body Composition
MH  - Body Mass Index
MH  - Croatia
MH  - Cross-Sectional Studies
MH  - *Exercise
MH  - Exercise Tolerance/*physiology
MH  - Female
MH  - Forced Expiratory Volume
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Nutrition Assessment
MH  - *Nutritional Status
MH  - Prealbumin/metabolism
MH  - Pulmonary Disease, Chronic Obstructive/epidemiology/metabolism/*physiopathology
MH  - Surveys and Questionnaires
MH  - Thinness/epidemiology
MH  - Vital Capacity
MH  - Vitamin D/blood
MH  - Walk Test
MH  - Walking Speed
OTO - NOTNLM
OT  - Chronic obstructive pulmonary disease
OT  - body composition
OT  - exercise capacity
OT  - nutritional status
OT  - physical activity
EDAT- 2017/11/04 06:00
MHDA- 2018/07/25 06:00
CRDT- 2017/11/04 06:00
PHST- 2017/11/04 06:00 [pubmed]
PHST- 2018/07/25 06:00 [medline]
PHST- 2017/11/04 06:00 [entrez]
AID - 10.1080/15412555.2017.1386643 [doi]
PST - ppublish
SO  - COPD. 2017 Dec;14(6):626-634. doi: 10.1080/15412555.2017.1386643. Epub 2017 Nov 
      3.