PMID- 29100465
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180801
LR  - 20180801
IS  - 1520-5827 (Electronic)
IS  - 0743-7463 (Linking)
VI  - 33
IP  - 47
DP  - 2017 Nov 28
TI  - Capsaicin-Inspired Thiol-Ene Terpolymer Networks Designed for Antibiofouling 
      Coatings.
PG  - 13689-13698
LID - 10.1021/acs.langmuir.7b03098 [doi]
AB  - Novel photocurable ternary polymer networks were prepared by incorporating 
      N-(4-hydroxy-3-methoxybenzyl)-acrylamide (HMBA) into a cross-linked thiol-ene 
      network based on poly(ethylene glycol)diacrylate (PEGDA) and 
      (mercaptopropyl)methylsiloxane homopolymers (MSHP). The ternary network materials 
      displayed bactericidal activity against Escherichia coli and Staphylococcus 
      aureus and reduced the attachment of marine organism Phaeodactylum tricornutum. 
      Extensive soaking of the polymer networks in aqueous solution indicated that no 
      active antibacterial component leached out of the materials, and thus the ternary 
      thiol-ene coating killed the bacteria by surface contact. The surface structures 
      of the polymer networks with varied content ratios were studied by sum frequency 
      generation (SFG) vibrational spectroscopy. The results demonstrated that the PDMS 
      Si-CH(3) groups and mimic-capsaicine groups are predominantly present at the 
      polymer-air interface of the coatings. Surface reorganization was apparent after 
      polymers were placed in contact with D(2)O: the hydrophobic PDMS Si-CH(3) groups 
      left the surface and returned to the bulk of the polymer networks, and the 
      hydrophilic PEG chains cover the polymer surfaces in D(2)O. The capasaicine 
      methoxy groups are able to segregate to the surface in an aqueous environment, 
      depending upon the ratio of HMBA/PEGDA. SFG measurements in situ showed that the 
      antibacterial HMBA chains, rather than the nonfouling PEG, played a dominant role 
      in mediating the antibiofouling performance in this particular polymer system.
FAU - Wang, Haiye
AU  - Wang H
AUID- ORCID: 0000-0002-1928-2883
AD  - College of Materials Science and Engineering, Donghua University , Shanghai 
      201620, P. R. China.
AD  - Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, 
      United States.
FAU - Jasensky, Joshua
AU  - Jasensky J
AUID- ORCID: 0000-0002-7370-0265
AD  - Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, 
      United States.
FAU - Ulrich, Nathan W
AU  - Ulrich NW
AUID- ORCID: 0000-0003-1763-9268
AD  - Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, 
      United States.
FAU - Cheng, Junjie
AU  - Cheng J
AD  - Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, 
      United States.
FAU - Huang, Hao
AU  - Huang H
AD  - Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, 
      United States.
FAU - Chen, Zhan
AU  - Chen Z
AD  - Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, 
      United States.
FAU - He, Chunju
AU  - He C
AD  - College of Materials Science and Engineering, Donghua University , Shanghai 
      201620, P. R. China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20171116
PL  - United States
TA  - Langmuir
JT  - Langmuir : the ACS journal of surfaces and colloids
JID - 9882736
EDAT- 2017/11/05 06:00
MHDA- 2017/11/05 06:01
CRDT- 2017/11/05 06:00
PHST- 2017/11/05 06:00 [pubmed]
PHST- 2017/11/05 06:01 [medline]
PHST- 2017/11/05 06:00 [entrez]
AID - 10.1021/acs.langmuir.7b03098 [doi]
PST - ppublish
SO  - Langmuir. 2017 Nov 28;33(47):13689-13698. doi: 10.1021/acs.langmuir.7b03098. Epub 
      2017 Nov 16.