PMID- 29103596
OWN - NLM
STAT- MEDLINE
DCOM- 20180131
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1528
DP  - 2017 Dec 15
TI  - Simultaneous determination of three pesticide adjuvant residues in plant-derived 
      agro-products using liquid chromatography-tandem mass spectrometry.
PG  - 53-60
LID - S0021-9673(17)31616-3 [pii]
LID - 10.1016/j.chroma.2017.10.075 [doi]
AB  - Herein, an accurate and reliable isotope-labelled internal standard method was 
      developed and validated for simultaneous determination of three polar pesticide 
      adjuvants, namely 2-pyrrolidone, N-methyl-2-pyrrolidone, and 
      N-ethyl-2-pyrrolidone in plant-derived agro-products. Matrices, including apple, 
      cabbage, tomato, cucumber, rice, and wheat were extracted with a modified quick, 
      easy, cheap, effective, rugged, and safe "QuEChERS" method and purified with a 
      new clean-up sorbent (Z-Sep). A hydrophilic interaction liquid chromatography 
      column (HILIC), exhibiting a lipophilic-hydrophilic character, was used to 
      separate the three analytes over 10min using liquid chromatography-tandem mass 
      spectrometry (LC-MS/MS). Matrix effects in various matrices were evaluated and an 
      isotope-labelled internal standard method was employed to compensate for ion 
      enhancement/suppression effects. At three fortification levels (2.0, 5.0, and 
      20.0mug/kg), the mean recoveries ranged from 78.5 to 112.1% with relative standard 
      deviations (RSDs)<11.0% for all tested analytes. The limits of detection (LODs) 
      and quantification (LOQs) were 0.04-0.45 and 0.12-1.58mug/kg in various matrices, 
      respectively. The developed experimental protocol was successfully applied to 
      monitor different samples purchased from local markets in Beijing, China. In 
      conclusion, the developed method exhibited both high sensitivity and satisfactory 
      accuracy and is suitable for the simultaneous determination of the three tested 
      pesticide adjuvant residues in agro-products of plant origin.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Li, Hui
AU  - Li H
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China.
FAU - Jiang, Zejun
AU  - Jiang Z
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China.
FAU - Cao, Xiaolin
AU  - Cao X
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China.
FAU - Su, Hang
AU  - Su H
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China.
FAU - Shao, Hua
AU  - Shao H
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China.
FAU - Jin, Fen
AU  - Jin F
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China.
FAU - Abd El-Aty, A M
AU  - Abd El-Aty AM
AD  - Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, 
      12211, Giza, Egypt; Department of Veterinary Pharmacology and Toxicology, College 
      of Veterinary Medicine, Konkuk University, Seoul, 143-701, Republic of Korea.
FAU - Wang, Jing
AU  - Wang J
AD  - Institute of Quality Standard and Testing Technology for Agro-products, Chinese 
      Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and 
      Safety, Ministry of Agriculture, Beijing, 100081, PR China. Electronic address: 
      w_jing2001@126.com.
LA  - eng
PT  - Journal Article
DEP - 20171102
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Beijing
MH  - Brassica/chemistry
MH  - *Chromatography, Liquid
MH  - Crops, Agricultural/*chemistry
MH  - Cucumis sativus/chemistry
MH  - Food Analysis/*methods
MH  - Limit of Detection
MH  - Pesticide Residues/*analysis
MH  - *Tandem Mass Spectrometry
OTO - NOTNLM
OT  - Isotope-labelled internal standard
OT  - Liquid chromatography-tandem mass spectrometry
OT  - Pesticide adjuvant
OT  - Plant-derived agro-product
OT  - QuEChERS
EDAT- 2017/11/07 06:00
MHDA- 2018/02/01 06:00
CRDT- 2017/11/07 06:00
PHST- 2017/07/02 00:00 [received]
PHST- 2017/10/27 00:00 [revised]
PHST- 2017/10/30 00:00 [accepted]
PHST- 2017/11/07 06:00 [pubmed]
PHST- 2018/02/01 06:00 [medline]
PHST- 2017/11/07 06:00 [entrez]
AID - S0021-9673(17)31616-3 [pii]
AID - 10.1016/j.chroma.2017.10.075 [doi]
PST - ppublish
SO  - J Chromatogr A. 2017 Dec 15;1528:53-60. doi: 10.1016/j.chroma.2017.10.075. Epub 
      2017 Nov 2.