PMID- 29105999
OWN - NLM
STAT- MEDLINE
DCOM- 20190527
LR  - 20190527
IS  - 1552-4965 (Electronic)
IS  - 1549-3296 (Linking)
VI  - 106
IP  - 3
DP  - 2018 Mar
TI  - Fabrication of interconnected porous beta-tricalcium phosphate (beta-TCP) based on a 
      setting reaction of beta-TCP granules with HNO(3) followed by heat treatment.
PG  - 797-804
LID - 10.1002/jbm.a.36285 [doi]
AB  - beta-Tricalcium phosphate [beta-TCP] is the typical bone substitute due to its 
      excellent osteoconductivity and bioresorbability. One of the keys to improve its 
      potential as bone substitute is to introduce porous structure and its regulation. 
      In this study, interconnected porous beta-TCP blocks were fabricated through a 
      setting reaction of beta-TCP granules and subsequent heat treatment. First, beta-TCP 
      granules were mixed with HNO(3) . Upon mixing, beta-TCP granules were bridged with 
      dicalcium phosphate dihydrate [DCPD: CaHPO(4) .2H(2) O] containing Ca(NO(3) )(2) 
      . Then, the DCPD-bridged beta-TCP was heated at 1100 degrees C. During the heating process, 
      DCPD containing Ca(NO(3) )(2) transformed into beta-TCP and bonded with beta-TCP 
      granules. As a result, an interconnected porous beta-TCP block formed. The diametral 
      tensile strength and porosity of the interconnected porous beta-TCP block fabricated 
      from 200-300-mum beta-TCP granules and 5 N HNO(3) and then heated at 1,100 degrees C were 
      1.4 +/- 0.2 MPa and 57% +/- 2%, respectively. (c) 2017 Wiley Periodicals, Inc. J Biomed 
      Mater Res Part A: 106A: 797-804, 2018.
CI  - (c) 2017 Wiley Periodicals, Inc.
FAU - Ishikawa, Kunio
AU  - Ishikawa K
AD  - Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 
      Maidashi, Fukuoka, Higashi-ku, 812-8582, Japan.
FAU - Putri, Tansza Setiana
AU  - Putri TS
AD  - Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 
      Maidashi, Fukuoka, Higashi-ku, 812-8582, Japan.
FAU - Tsuchiya, Akira
AU  - Tsuchiya A
AD  - Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 
      Maidashi, Fukuoka, Higashi-ku, 812-8582, Japan.
FAU - Tanaka, Keisuke
AU  - Tanaka K
AD  - Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 
      Maidashi, Fukuoka, Higashi-ku, 812-8582, Japan.
FAU - Tsuru, Kanji
AU  - Tsuru K
AD  - Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 
      Maidashi, Fukuoka, Higashi-ku, 812-8582, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171127
PL  - United States
TA  - J Biomed Mater Res A
JT  - Journal of biomedical materials research. Part A
JID - 101234237
RN  - 0 (Calcium Phosphates)
RN  - 0 (beta-tricalcium phosphate)
RN  - 411VRN1TV4 (Nitric Acid)
SB  - IM
MH  - Calcium Phosphates/*chemistry
MH  - Differential Thermal Analysis
MH  - *Hot Temperature
MH  - Nitric Acid/*chemistry
MH  - Porosity
MH  - Tensile Strength
MH  - Thermogravimetry
MH  - X-Ray Diffraction
MH  - X-Ray Microtomography
OTO - NOTNLM
OT  - biomaterial
OT  - bone substitute
OT  - porous structure
OT  - beta-tricalcium phosphate
EDAT- 2017/11/07 06:00
MHDA- 2019/05/28 06:00
CRDT- 2017/11/07 06:00
PHST- 2017/08/28 00:00 [received]
PHST- 2017/10/16 00:00 [revised]
PHST- 2017/11/02 00:00 [accepted]
PHST- 2017/11/07 06:00 [pubmed]
PHST- 2019/05/28 06:00 [medline]
PHST- 2017/11/07 06:00 [entrez]
AID - 10.1002/jbm.a.36285 [doi]
PST - ppublish
SO  - J Biomed Mater Res A. 2018 Mar;106(3):797-804. doi: 10.1002/jbm.a.36285. Epub 
      2017 Nov 27.