PMID- 29106812 OWN - NLM STAT- MEDLINE DCOM- 20180918 LR - 20180918 IS - 1715-5320 (Electronic) IS - 1715-5312 (Linking) VI - 43 IP - 4 DP - 2018 Apr TI - Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females. PG - 324-330 LID - 10.1139/apnm-2017-0412 [doi] AB - A number of different forms of protein and their analogues have been investigated for their efficacy in ameliorating exercise-induced muscle damage (EIMD) and recovery. Preliminary data regarding whey protein hydrolysate (WPH) supplementation are promising. However, its efficacy beyond acute eccentric/resistance exercise bouts or longer term training programmes are limited and all investigations have been conducted in male or mixed-sex groups. This study sought to elucidate whether the benefits of WPH previously reported can be demonstrated in females following repeated-sprint exercise. Twenty physically active females were assigned to consume 2 doses of 70 mL WPH or isoenergetic carbohydrate (CHO) for 4 days post-EIMD. Measures of muscle soreness, limb girth, flexibility, muscle function, and creatine kinase were collected before, immediately after, and 24, 48, and 72 h postexercise. Time effects were observed for all variables (p < 0.05) except limb girth, which is indicative of EIMD. Flexibility improved beyond baseline measures following WPH by 72 h, but had failed to recover in the CHO group (p = 0.011). Reactive strength index was higher throughout recovery in the WPH group compared with CHO (p = 0.016). Reductions in creatine kinase were greater following WPH compared with CHO at 48 h post-EIMD (p = 0.031). The findings suggest that 4-day supplementation of WPH is beneficial for reducing symptoms of EIMD and improving recovery of muscle function in physically active females. FAU - Brown, Meghan A AU - Brown MA AD - a School of Sport and Exercise, University of Gloucestershire, Gloucester, GL2 9HW, UK. AD - b Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK. FAU - Stevenson, Emma J AU - Stevenson EJ AD - c Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle, NE2 4HH, UK. FAU - Howatson, Glyn AU - Howatson G AD - d Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK. AD - e Water Research Group, School of Environmental Sciences and Development, Northwest University, Potchefstroom, South Africa. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20171106 PL - Canada TA - Appl Physiol Nutr Metab JT - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme JID - 101264333 RN - 0 (Dietary Carbohydrates) RN - 0 (Protein Hydrolysates) RN - 0 (Whey Proteins) SB - IM MH - Dietary Carbohydrates/administration & dosage/metabolism MH - *Dietary Supplements/adverse effects MH - Double-Blind Method MH - England MH - *Exercise MH - Female MH - Humans MH - *Muscle Contraction MH - *Muscle Strength MH - Muscle, Skeletal/*metabolism/pathology/physiopathology MH - Muscular Diseases/*diet therapy/etiology/metabolism/physiopathology MH - Protein Hydrolysates/*administration & dosage/adverse effects/metabolism MH - Recovery of Function MH - Running MH - Sex Factors MH - Time Factors MH - Treatment Outcome MH - Whey Proteins/*administration & dosage/adverse effects/metabolism MH - Young Adult OTO - NOTNLM OT - creatine kinase OT - creatine kinase OT - flexibilite des ischiojambiers OT - hamstring flexibility OT - indice de force reactive OT - reactive strength index OT - repeated sprint OT - sprint repete EDAT- 2017/11/07 06:00 MHDA- 2018/09/19 06:00 CRDT- 2017/11/07 06:00 PHST- 2017/11/07 06:00 [pubmed] PHST- 2018/09/19 06:00 [medline] PHST- 2017/11/07 06:00 [entrez] AID - 10.1139/apnm-2017-0412 [doi] PST - ppublish SO - Appl Physiol Nutr Metab. 2018 Apr;43(4):324-330. doi: 10.1139/apnm-2017-0412. Epub 2017 Nov 6.