PMID- 29108487 OWN - NLM STAT- MEDLINE DCOM- 20191009 LR - 20240328 IS - 2045-7723 (Electronic) IS - 1079-0268 (Print) IS - 1079-0268 (Linking) VI - 41 IP - 3 DP - 2018 May TI - A clinically meaningful training effect in walking speed using functional electrical stimulation for motor-incomplete spinal cord injury. PG - 361-366 LID - 10.1080/10790268.2017.1392106 [doi] AB - CONTEXT/OBJECTIVE: The study aimed to investigate the presence of a training effect for rehabilitation of walking function in motor-incomplete spinal cord injury (SCI) through daily use of functional electrical stimulation (FES). SETTING: A specialist FES outpatient centre. PARTICIPANTS: Thirty-five participants (mean age 53, SD 15, range 18-80; mean years since diagnosis 9, range 5 months - 39 years) with drop foot and motor-incomplete SCI (T12 or higher, ASIA Impairment Scale C and D) able to ambulate 10 metres with the use of a walking stick or frame. INTERVENTIONS: FES of the peroneal nerve, glutei and hamstrings as clinically indicated over six months in the community. OUTCOME MEASURES: The data was analysed for a training effect (difference between unassisted ten metre walking speed at baseline and after six months) and orthotic effects (difference between walking speed with and without FES) initially on day one and after six months. The data was further analysed for a minimum clinically important difference (MCID) (>0.06 m/s). RESULTS: A clinically meaningful, significant change was observed for initial orthotic effect (0.13m/s, CI: 0.04-0.17, P = 0.013), total orthotic effect (0.11m/s, CI: 0.04-0.18, P = 0.017) and training effect (0.09m/s, CI: 0.02-0.16, P = 0.025). CONCLUSION: The results suggest that daily independent use of FES may produce clinically meaningful changes in walking speed which are significant for motor-incomplete SCI. Further research exploring the mechanism for the presence of a training effect may be beneficial in targeting therapies for future rehabilitation. FAU - Street, Tamsyn AU - Street T AUID- ORCID: 0000-0002-9859-6732 AD - a Clinical Science and Engineering , Salisbury NHS Foundation Trust , Salisbury , UK. FAU - Singleton, Christine AU - Singleton C AD - b West Midlands Rehabilitation Centre , Birmingham Community Healthcare NHS , Birmingham , UK. LA - eng PT - Journal Article DEP - 20171106 PL - England TA - J Spinal Cord Med JT - The journal of spinal cord medicine JID - 9504452 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Exercise Therapy/instrumentation/*methods MH - Female MH - Humans MH - Male MH - Middle Aged MH - Muscle, Skeletal/innervation/physiopathology MH - Neurological Rehabilitation/*methods MH - Orthotic Devices MH - Peroneal Nerve/physiopathology MH - Spinal Cord Injuries/pathology/*rehabilitation MH - Transcutaneous Electric Nerve Stimulation/*methods MH - *Walking Speed PMC - PMC6055946 OTO - NOTNLM OT - Functional electrical stimulation OT - Peroneal nerve stimulation OT - Spinal cord injury OT - Training effect EDAT- 2017/11/08 06:00 MHDA- 2019/10/11 06:00 PMCR- 2019/05/01 CRDT- 2017/11/08 06:00 PHST- 2017/11/08 06:00 [pubmed] PHST- 2019/10/11 06:00 [medline] PHST- 2017/11/08 06:00 [entrez] PHST- 2019/05/01 00:00 [pmc-release] AID - yscm-41-361 [pii] AID - 10.1080/10790268.2017.1392106 [doi] PST - ppublish SO - J Spinal Cord Med. 2018 May;41(3):361-366. doi: 10.1080/10790268.2017.1392106. Epub 2017 Nov 6.