PMID- 29112173 OWN - NLM STAT- MEDLINE DCOM- 20180618 LR - 20220409 IS - 1420-3049 (Electronic) IS - 1420-3049 (Linking) VI - 22 IP - 11 DP - 2017 Nov 7 TI - Chemical Fingerprint and Multicomponent Quantitative Analysis for the Quality Evaluation of Cyclocarya paliurus Leaves by HPLC-Q-TOF-MS. LID - 10.3390/molecules22111927 [doi] LID - 1927 AB - Cyclocarya paliurus is an edible and medicinal plant containing various bioactive components with significant health benefits. A combinative method using high-performance liquid chromatography (HPLC) fingerprint and quantitative analysis was developed and successfully applied for characterization and quality evaluation of C. paliurus leaves collected from 18 geographical locations of China. For the fingerprint analysis, 21 common peaks were observed among the 18 samples, and these peaks were identified by high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS), while a simultaneous quantification of 16 markers was conducted to interpret the variations of contents of these bioactive compounds among the C. paliurus leaves from different geographical locations. Quantification results showed that the contents of these sixteen investigated compounds varied greatly among the leaves from different locations. The developed new method would be a valuable reference for further study and development of this bioactive plant. FAU - Cao, Yanni AU - Cao Y AD - College of Forestry, Nanjing Forestry University, Nanjing 210037, China. 182cyn@sina.com. FAU - Fang, Shengzuo AU - Fang S AD - College of Forestry, Nanjing Forestry University, Nanjing 210037, China. fangsz@njfu.edu.cn. AD - Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China. fangsz@njfu.edu.cn. FAU - Yin, Zhiqi AU - Yin Z AD - Department of Natural Medicinal Chemistry and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 10009, China. chyzq2005@126.com. FAU - Fu, Xiangxiang AU - Fu X AD - College of Forestry, Nanjing Forestry University, Nanjing 210037, China. xxfu@njfu.edu.cn. AD - Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China. xxfu@njfu.edu.cn. FAU - Shang, Xulan AU - Shang X AD - College of Forestry, Nanjing Forestry University, Nanjing 210037, China. shangxulan@njfu.edu.cn. AD - Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China. shangxulan@njfu.edu.cn. FAU - Yang, Wanxia AU - Yang W AD - College of Forestry, Nanjing Forestry University, Nanjing 210037, China. yangwanxia@njfu.com.cn. AD - Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China. yangwanxia@njfu.com.cn. FAU - Yang, Huimin AU - Yang H AD - Department of Natural Medicinal Chemistry and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 10009, China. yanghuimin607@163.com. LA - eng PT - Journal Article DEP - 20171107 PL - Switzerland TA - Molecules JT - Molecules (Basel, Switzerland) JID - 100964009 RN - 0 (Plant Extracts) SB - IM MH - Chromatography, High Pressure Liquid MH - Juglandaceae/*chemistry MH - Mass Spectrometry MH - Molecular Structure MH - Plant Extracts/*chemistry MH - Plant Leaves/chemistry PMC - PMC6150387 OTO - NOTNLM OT - Cyclocarya paliurus OT - HPLC-Q-TOF-MS OT - fingerprint OT - quality evaluation OT - quantitative analysis COIS- The authors declare no conflict of interest. EDAT- 2017/11/08 06:00 MHDA- 2018/06/19 06:00 PMCR- 2017/11/07 CRDT- 2017/11/08 06:00 PHST- 2017/10/22 00:00 [received] PHST- 2017/11/04 00:00 [revised] PHST- 2017/11/06 00:00 [accepted] PHST- 2017/11/08 06:00 [entrez] PHST- 2017/11/08 06:00 [pubmed] PHST- 2018/06/19 06:00 [medline] PHST- 2017/11/07 00:00 [pmc-release] AID - molecules22111927 [pii] AID - molecules-22-01927 [pii] AID - 10.3390/molecules22111927 [doi] PST - epublish SO - Molecules. 2017 Nov 7;22(11):1927. doi: 10.3390/molecules22111927.