PMID- 29113074
OWN - NLM
STAT- MEDLINE
DCOM- 20180619
LR  - 20240327
IS  - 1422-0067 (Electronic)
IS  - 1422-0067 (Linking)
VI  - 18
IP  - 11
DP  - 2017 Nov 5
TI  - Simultaneous Determination and Investigation of Nine Fungicides in Fruits Using 
      Diethylenetriamine-Functional Magnetic Core-Shell Polymer Modified Graphene Oxide 
      as an Efficient Adsorbent Coupled to UPLC-HRMS.
LID - 10.3390/ijms18112333 [doi]
LID - 2333
AB  - In this study, diethylenetriamine-functional magnetic core-shell polymer modified 
      graphene oxide (DETA-MPs-GO) was prepared via precipitation polymerization and 
      amidation reaction, and it was characterized by transmission electron microscopy 
      (TEM), Fourier-transformed infrared spectroscopy (FTIR), and X-ray diffractometer 
      (XRD). Subsequently, a magnetic solid-phase extraction (MSPE) procedure was 
      applied to the as-synthesized DETA-MPs-GO for the detection of nine fungicides in 
      fruit samples, prior to ultra-performance liquid chromatography-high resolution 
      mass spectrometry (UPLC-HRMS). The homogenized fruit samples, spiked with 
      D-labelled internal standards, were firstly extracted by 5 mL of acetonitrile 
      twice and then purified by DETA-MPs-GO adsorbents. The optimization of the 
      adsorption and elution conditions of DETA-MPs-GO toward fungicides was carried 
      out to attain a satisfactory adsorption performance and desorption efficiency. 
      The adsorption mechanism was carefully investigated, and the results revealed 
      that a synergistic adsorption mechanism, including hydrogen bond and a pi-pi 
      stacking interaction, was confirmed. Moreover, the limits of quantitation (LOQs) 
      of the proposed approach were in the range of 0.01 to 0.30 mug/kg under the 
      optimum conditions. The average recoveries at three spiking levels were 84.9% to 
      105.2%, with relative standard deviations (RSDs) varying from 0.8% to 8.2% (n = 
      6). The developed method was successfully utilized for the screening and 
      detection of fungicides in 81 fruit samples purchased from markets. A detailed 
      survey was carried out about the concentration distribution, types of fungicides, 
      and combined use of fungicides in different fruits.
FAU - Ye, Ming-Li
AU  - Ye ML
AD  - Department of Chemistry, Zhejiang University, Hangzhou 310028, China. 
      systemview123@126.com.
FAU - Zhu, Yan
AU  - Zhu Y
AD  - Department of Chemistry, Zhejiang University, Hangzhou 310028, China. 
      zhuyan@zju.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20171105
PL  - Switzerland
TA  - Int J Mol Sci
JT  - International journal of molecular sciences
JID - 101092791
RN  - 0 (Antifungal Agents)
RN  - 0 (Polyamines)
RN  - 03K6SX4V2J (diethylenetriamine)
RN  - 7782-42-5 (Graphite)
SB  - IM
MH  - Antifungal Agents/*analysis/chemistry
MH  - Food Analysis/*methods
MH  - Fruit/chemistry/*standards
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Graphite/*chemistry
MH  - Polyamines/chemistry
PMC - PMC5713302
OTO - NOTNLM
OT  - diethylenetriamine-functional magnetic core-shell polymer modified graphene oxide 
      (DETA-MPs-GO)
OT  - fungicides
OT  - magnetic solid-phase extraction (MSPE)
OT  - synergistic adsorption mechanism
OT  - ultra-performance liquid chromatography-high resolution mass spectrometry 
      (UPLC-HRMS)
COIS- The authors declare no conflict of interest.
EDAT- 2017/11/09 06:00
MHDA- 2018/06/21 06:00
PMCR- 2017/11/01
CRDT- 2017/11/09 06:00
PHST- 2017/10/10 00:00 [received]
PHST- 2017/10/28 00:00 [revised]
PHST- 2017/11/02 00:00 [accepted]
PHST- 2017/11/09 06:00 [entrez]
PHST- 2017/11/09 06:00 [pubmed]
PHST- 2018/06/21 06:00 [medline]
PHST- 2017/11/01 00:00 [pmc-release]
AID - ijms18112333 [pii]
AID - ijms-18-02333 [pii]
AID - 10.3390/ijms18112333 [doi]
PST - epublish
SO  - Int J Mol Sci. 2017 Nov 5;18(11):2333. doi: 10.3390/ijms18112333.