PMID- 29114016
OWN - NLM
STAT- MEDLINE
DCOM- 20190423
LR  - 20191210
IS  - 1532-298X (Electronic)
IS  - 1040-4651 (Print)
IS  - 1040-4651 (Linking)
VI  - 29
IP  - 12
DP  - 2017 Dec
TI  - EIN3 and PIF3 Form an Interdependent Module That Represses Chloroplast 
      Development in Buried Seedlings.
PG  - 3051-3067
LID - 10.1105/tpc.17.00508 [doi]
AB  - In buried seedlings, chloroplasts are arrested at the etioplast stage, but they 
      rapidly mature upon emergence of the seedling. Etioplast-chloroplast 
      differentiation is halted through the integration of soil-induced signals, 
      including pressure and the absence of light, although the details on how this 
      information converges to regulate cellular decisions remain unclear. Here, we 
      identify an interdependent transcription module that integrates the mechanical 
      pressure and darkness signals to control chloroplast development in Arabidopsis 
      thaliana Mutations of ETHYLENE-INSENSITIVE3 (EIN3), the primary transcription 
      factor in the ethylene signaling pathway that is activated in response to 
      mechanical pressure, cause early development of etioplasts in the dark and severe 
      photobleaching upon light exposure. Genetic studies demonstrate that repression 
      of etioplast differentiation by EIN3 requires PHYTOCHROME INTERACTING FACTOR3 
      (PIF3), a darkness-stabilized bHLH transcription factor. EIN3 and PIF3 directly 
      interact and form an interdependent module to repress the expression of most 
      LIGHT HARVESTING COMPLEX (LHC) genes; overexpressing even one LHC could cause 
      premature development of etioplasts. The EIN3-PIF3 transcription module 
      synergistically halts chloroplast development by interdependently co-occupying 
      the promoters of LHC genes. Thus, our results define a transcriptional regulatory 
      module and provide mechanistic insight on the concerted regulation of chloroplast 
      development by multiple soil-induced signals.
CI  - (c) 2017 American Society of Plant Biologists. All rights reserved.
FAU - Liu, Xiaoqin
AU  - Liu X
AD  - College of Life Sciences, Capital Normal University, Beijing 100048, China.
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China.
FAU - Liu, Renlu
AU  - Liu R
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China.
FAU - Li, Yue
AU  - Li Y
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China.
FAU - Shen, Xing
AU  - Shen X
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China.
FAU - Zhong, Shangwei
AU  - Zhong S
AUID- ORCID: 0000-0002-6370-8095
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China shangwei.zhong@pku.edu.cn hui.shi@cnu.edu.cn.
FAU - Shi, Hui
AU  - Shi H
AUID- ORCID: 0000-0002-2349-2381
AD  - College of Life Sciences, Capital Normal University, Beijing 100048, China 
      shangwei.zhong@pku.edu.cn hui.shi@cnu.edu.cn.
AD  - State Key Laboratory of Protein and Plant Gene Research, School of Advanced 
      Agricultural Sciences and School of Life Sciences, Peking University, Beijing 
      100871, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171107
PL  - England
TA  - Plant Cell
JT  - The Plant cell
JID - 9208688
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Basic Helix-Loop-Helix Transcription Factors)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (EIN3 protein, Arabidopsis)
RN  - 0 (Nuclear Proteins)
RN  - 0 (PIF3 protein, Arabidopsis)
RN  - 0 (Transcription Factors)
RN  - 20369-67-9 (Protochlorophyllide)
SB  - IM
CIN - Plant Cell. 2017 Dec;29(12):2951-2952. PMID: 29212840
MH  - Arabidopsis/genetics/*metabolism/radiation effects/ultrastructure
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - Basic Helix-Loop-Helix Transcription Factors/genetics/*metabolism
MH  - Chloroplasts/*metabolism/radiation effects/ultrastructure
MH  - DNA-Binding Proteins
MH  - Etiolation/radiation effects
MH  - Gene Expression Regulation, Plant/radiation effects
MH  - Genes, Plant
MH  - Light
MH  - Nuclear Proteins/genetics/*metabolism
MH  - Oxidation-Reduction
MH  - Oxidative Stress/radiation effects
MH  - Promoter Regions, Genetic
MH  - Protein Binding/radiation effects
MH  - Protein Stability/radiation effects
MH  - Protochlorophyllide/metabolism
MH  - Seedlings/*metabolism/radiation effects/ultrastructure
MH  - Transcription Factors/genetics/*metabolism
MH  - Transcriptome/genetics
PMC - PMC5757274
EDAT- 2017/11/09 06:00
MHDA- 2019/04/24 06:00
PMCR- 2018/12/01
CRDT- 2017/11/09 06:00
PHST- 2017/07/05 00:00 [received]
PHST- 2017/10/02 00:00 [revised]
PHST- 2017/11/04 00:00 [accepted]
PHST- 2017/11/09 06:00 [pubmed]
PHST- 2019/04/24 06:00 [medline]
PHST- 2017/11/09 06:00 [entrez]
PHST- 2018/12/01 00:00 [pmc-release]
AID - tpc.17.00508 [pii]
AID - TPC2017RA00508R1 [pii]
AID - 10.1105/tpc.17.00508 [doi]
PST - ppublish
SO  - Plant Cell. 2017 Dec;29(12):3051-3067. doi: 10.1105/tpc.17.00508. Epub 2017 Nov 
      7.