PMID- 29115157 OWN - NLM STAT- MEDLINE DCOM- 20200709 LR - 20200709 IS - 1552-3799 (Electronic) IS - 1054-7738 (Linking) VI - 28 IP - 5 DP - 2019 Jun TI - Symptom Burden Clustering in Chronic Kidney Disease Stage 5. PG - 583-601 LID - 10.1177/1054773817740671 [doi] AB - Patients with chronic kidney disease (CKD) Stage 5, experience multiple symptoms that negatively affect the health-related quality of life (HRQoL). This study examined the cluster of symptoms and their association with disease severity and comorbidities. The study sample included 123 patients with CKD Stage 5; 60 patients were in the dialysis group and 63 patients in the Conservative Kidney Management group. Symptom data were collected using the Spanish modified version of Palliative Care Outcome Scale-Symptoms (POS-S) Renal, a validated questionnaire to assess symptoms in this population. More than half of the patients described weakness, difficulty sleeping, and feeling depressed. Two symptom clusters were identified. There was no significant statistical correlation between disease severity and symptoms and between comorbidities and symptoms. The tendency of these symptoms to occur together has implications for improving symptom management in this population. Routine symptom assessment can be useful in clinical and research settings. FAU - Gutierrez Sanchez, Daniel AU - Gutierrez Sanchez D AD - 1 Cudeca Foundation, Malaga, Spain. FAU - Leiva-Santos, Juan P AU - Leiva-Santos JP AD - 2 Hospital of Manacor, Manacor, Spain. FAU - Cuesta-Vargas, Antonio I AU - Cuesta-Vargas AI AD - 3 University of Malaga, Malaga, Spain. AD - 4 Queensland University of Technology, Brisbane, Australia. LA - eng PT - Journal Article DEP - 20171108 PL - United States TA - Clin Nurs Res JT - Clinical nursing research JID - 9208508 MH - Aged MH - Comorbidity MH - Cross-Sectional Studies MH - Depression/psychology MH - Female MH - Humans MH - Kidney Failure, Chronic/*therapy MH - Male MH - Middle Aged MH - Pain/psychology MH - Palliative Care/*psychology MH - Quality of Life/*psychology MH - Renal Dialysis MH - *Severity of Illness Index MH - Spain MH - Surveys and Questionnaires MH - *Symptom Assessment OTO - NOTNLM OT - advanced chronic kidney disease OT - nursing OT - symptom cluster OT - symptom evaluation EDAT- 2017/11/09 06:00 MHDA- 2020/07/10 06:00 CRDT- 2017/11/09 06:00 PHST- 2017/11/09 06:00 [pubmed] PHST- 2020/07/10 06:00 [medline] PHST- 2017/11/09 06:00 [entrez] AID - 10.1177/1054773817740671 [doi] PST - ppublish SO - Clin Nurs Res. 2019 Jun;28(5):583-601. doi: 10.1177/1054773817740671. Epub 2017 Nov 8.