PMID- 29119456
OWN - NLM
STAT- MEDLINE
DCOM- 20180910
LR  - 20181202
IS  - 1867-108X (Electronic)
IS  - 1867-1071 (Linking)
VI  - 36
IP  - 2
DP  - 2018 Feb
TI  - Heterogeneity of longitudinal and circumferential contraction in relation to late 
      gadolinium enhancement in hypertrophic cardiomyopathy patients with preserved 
      left ventricular ejection fraction.
PG  - 103-112
LID - 10.1007/s11604-017-0700-5 [doi]
AB  - PURPOSE: To evaluate heterogeneity of myocardial contraction in relation to 
      extensive late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) 
      patients with preserved left ventricular ejection fraction, using fast 
      strain-encoded magnetic resonance imaging. MATERIALS AND METHODS: Twenty-two HCM 
      patients and 24 age-matched control subjects were included in this retrospective 
      study. The regional and global peak values of longitudinal and circumferential 
      strain (LS(regional), LS(global), CS(regional), CS(global)), and their regional 
      heterogeneities were evaluated using coefficients of variation (LS(CoV), CS(CoV)) 
      in relation to LGE. Receiver operating characteristic curve analysis was 
      performed to identify patients with a total left ventricular myocardial 
      LGE >/= 15%. RESULTS: LS(global) in HCM patients was significantly decreased 
      compared to that in controls (- 14.4 +/- 2.4% vs - 17.2 +/- 2.0%; p = 0.0004), while 
      CS(global) was not (p = 1.0). Negative LGE segments demonstrated decreased 
      LS(regional) in HCM patients compared to in controls (p < 0.0001), while 
      CS(regional) was not decreased. CS(CoV) demonstrated the largest area under the 
      curve (AUC) (0.91), with high sensitivity (83%) and specificity (94%) for 
      detection of HCM patients with extensive LGE, while the AUC of LS(CoV) was low 
      (0.49). CONCLUSION: The heterogeneity in CS(regional) has a high diagnostic value 
      for detection of HCM patients with extensive LGE.
FAU - Sakamoto, Keita
AU  - Sakamoto K
AD  - Department of Diagnostic and Interventional Radiology, Hokkaido University 
      Hospital, Kita1 4, Nishi 5, Kita-ku, Sapporo, 060-8638, Japan.
AD  - Department of Radiation Medicine, Hokkaido University Graduate School of 
      Medicine, Sapporo, Japan.
FAU - Oyama-Manabe, Noriko
AU  - Oyama-Manabe N
AD  - Department of Diagnostic and Interventional Radiology, Hokkaido University 
      Hospital, Kita1 4, Nishi 5, Kita-ku, Sapporo, 060-8638, Japan. 
      norikooyama@med.hokudai.ac.jp.
FAU - Manabe, Osamu
AU  - Manabe O
AD  - Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, 
      Sapporo, Japan.
FAU - Aikawa, Tadao
AU  - Aikawa T
AD  - Department of Cardiovascular Medicine, Hokkaido University Graduate School of 
      Medicine, Sapporo, Japan.
FAU - Kikuchi, Yasuka
AU  - Kikuchi Y
AD  - Department of Diagnostic and Interventional Radiology, Hokkaido University 
      Hospital, Kita1 4, Nishi 5, Kita-ku, Sapporo, 060-8638, Japan.
AD  - Center for Cause of Death Investigation, Hokkaido University Graduate School of 
      Medicine, Sapporo, Japan.
FAU - Sasai-Masuko, Harue
AU  - Sasai-Masuko H
AD  - Department of Cardiovascular Medicine, Hokkaido University Graduate School of 
      Medicine, Sapporo, Japan.
FAU - Naya, Masanao
AU  - Naya M
AD  - Department of Cardiovascular Medicine, Hokkaido University Graduate School of 
      Medicine, Sapporo, Japan.
FAU - Kudo, Kohsuke
AU  - Kudo K
AD  - Department of Diagnostic and Interventional Radiology, Hokkaido University 
      Hospital, Kita1 4, Nishi 5, Kita-ku, Sapporo, 060-8638, Japan.
FAU - Kato, Fumi
AU  - Kato F
AD  - Department of Diagnostic and Interventional Radiology, Hokkaido University 
      Hospital, Kita1 4, Nishi 5, Kita-ku, Sapporo, 060-8638, Japan.
FAU - Tamaki, Nagara
AU  - Tamaki N
AD  - Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
FAU - Shirato, Hiroki
AU  - Shirato H
AD  - Department of Radiation Medicine, Hokkaido University Graduate School of 
      Medicine, Sapporo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20171109
PL  - Japan
TA  - Jpn J Radiol
JT  - Japanese journal of radiology
JID - 101490689
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Area Under Curve
MH  - Cardiomyopathy, Hypertrophic/*diagnostic imaging/*physiopathology
MH  - Contrast Media
MH  - Female
MH  - *Gadolinium
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Image Processing, Computer-Assisted/methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Myocardial Contraction/*physiology
MH  - ROC Curve
MH  - Retrospective Studies
MH  - Time
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Circumferential strain
OT  - Hypertrophic cardiomyopathy
OT  - Late gadolinium enhancement
OT  - Longitudinal strain
OT  - Strain-encoded magnetic resonance imaging
EDAT- 2017/11/10 06:00
MHDA- 2018/09/11 06:00
CRDT- 2017/11/10 06:00
PHST- 2017/08/09 00:00 [received]
PHST- 2017/10/29 00:00 [accepted]
PHST- 2017/11/10 06:00 [pubmed]
PHST- 2018/09/11 06:00 [medline]
PHST- 2017/11/10 06:00 [entrez]
AID - 10.1007/s11604-017-0700-5 [pii]
AID - 10.1007/s11604-017-0700-5 [doi]
PST - ppublish
SO  - Jpn J Radiol. 2018 Feb;36(2):103-112. doi: 10.1007/s11604-017-0700-5. Epub 2017 
      Nov 9.